{
  "abstract": "We read with great interest the recent study by Gilliam-Vigh et al demonstrating significant transcriptomic alterations in the intestinal mucosa of individuals with type 2 diabetes (T2D), particularly increased immune activation, altered barrier function in the large intestine and metabolic dysfunction.1 These findings provide crucial mechanistic insights that complement observations on metabolic disturbances in patients with irritable bowel syndrome (IBS), supporting the rationale for glucose-targeted interventions.",
  "authors": [
    {
      "affiliations": [
        "Institute of Nutritional Medicine, University Hospital Schleswig-Holstein Lübeck Campus, Lübeck, Germany"
      ],
      "name": "Franziska Schmelter"
    },
    {
      "affiliations": [
        "Institute of Nutritional Medicine, University Hospital Schleswig-Holstein Lübeck Campus, Lübeck, Germany",
        "Perfood Laboratories GmbH, Lübeck, Germany"
      ],
      "name": "Torsten Schröder"
    },
    {
      "affiliations": [
        "Institute of Nutritional Medicine, University Hospital Schleswig-Holstein Lübeck Campus, Lübeck, Germany"
      ],
      "name": "Yves Laumonnier"
    },
    {
      "affiliations": [
        "Institute of Nutritional Medicine, University Hospital Schleswig-Holstein Lübeck Campus, Lübeck, Germany",
        "Perfood Laboratories GmbH, Lübeck, Germany",
        "Institute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany",
        "Department of Biomedical Sciences, University of Copenhagen Faculty of Health and Medical Sciences, Copenhagen, Denmark"
      ],
      "name": "OUTLIVE-CRC consortium"
    },
    {
      "affiliations": [
        "Institute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany"
      ],
      "name": "Stephan C Bischoff"
    },
    {
      "affiliations": [
        "Institute of Nutritional Medicine, University Hospital Schleswig-Holstein Lübeck Campus, Lübeck, Germany"
      ],
      "name": "Stefanie Derer"
    },
    {
      "affiliations": [
        "Department of Biomedical Sciences, University of Copenhagen Faculty of Health and Medical Sciences, Copenhagen, Denmark"
      ],
      "name": "Benjamin Anderschou Holbech Jensen"
    },
    {
      "affiliations": [
        "Institute of Nutritional Medicine, University Hospital Schleswig-Holstein Lübeck Campus, Lübeck, Germany"
      ],
      "name": "Christian Sina"
    }
  ],
  "title": "Impaired glucose metabolism in irritable bowel syndrome: personalised low-glycaemic diet as potential therapeutic target",
  "uid": "14cbe38f-a3d3-557e-8617-d1edd3d53c68"
}