{
  "abstract": "A subset of patients with oesophageal cancer shows a marked response to neoadjuvant chemoradiotherapy, yet post-treatment assessment by endoscopy or imaging remains unreliable. We report a 65-year-old patient with major morphological response after neoadjuvant FLOT chemotherapy, a regimen comprising 5-fluorouracil, leucovorin, oxaliplatin and docetaxel, for locally advanced gastro-oesophageal junction adenocarcinoma (tumour, node, metastases (TNM) classification: cT2N0M0), but possible residual disease. The patient chose endoscopic submucosal dissection (ESD) instead of completion surgery. Histology revealed complete response (ypT0). During 15 months of structured surveillance with serial endoscopic and radiological follow-up, the patient remained asymptomatic and disease-free, without local or distant recurrence. Further studies are needed to clarify the role of diagnostic endoscopic resection after uncertain response to neoadjuvant therapy.",
  "authors": [
    {
      "affiliations": [
        "Department of Oncological Gastroenterology, The Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Warsaw, Masovian, Poland"
      ],
      "name": "Aleksandra Sztogrin-Pluta"
    },
    {
      "affiliations": [
        "Department of Surgical Oncology, Transplant Surgery and General Surgery, Medical University of Gdańsk, Gdańsk, Poland, Gdański Uniwersytet Medyczny, Gdańsk, Pomeranian Voivodeship, Poland"
      ],
      "name": "Katarzyna Polomska"
    },
    {
      "affiliations": [
        "Department of Radiology, The Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Warsaw, Masovian Voivodeship, Poland"
      ],
      "name": "Joanna Podgorska"
    },
    {
      "affiliations": [
        "Department of Pathology, The Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Warsaw, Masovian Voivodeship, Poland",
        "Department of Gastroenterology, Hepatology and Clinical Oncology, Centre for Postgraduate Medical Education, Warsaw, Masovian Voivodeship, Poland"
      ],
      "name": "Andrzej Mroz"
    },
    {
      "affiliations": [
        "Department of Gastrointestinal Cancers and Neuroendocrine Tumors Surgery, The Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Warsaw, Masovian Voivodeship, Poland"
      ],
      "name": "Tomasz Olesinski"
    },
    {
      "affiliations": [
        "Department of Oncological Gastroenterology, The Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Warsaw, Masovian, Poland",
        "Department of Gastroenterology, Hepatology and Clinical Oncology, Centre for Postgraduate Medical Education, Warsaw, Masovian Voivodeship, Poland"
      ],
      "name": "Nastazja Dagny Pilonis"
    },
    {
      "affiliations": [
        "Department of Oncological Gastroenterology, The Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Warsaw, Masovian, Poland",
        "Department of Gastroenterology, Hepatology and Clinical Oncology, Centre for Postgraduate Medical Education, Warsaw, Masovian Voivodeship, Poland"
      ],
      "name": "Michal F Kaminski"
    }
  ],
  "title": "Diagnostic endoscopic resection for assessing potential residual disease after neoadjuvant therapy for oesophageal adenocarcinoma",
  "uid": "d33a587d-786a-59dd-bc9e-92ec04d00792"
}