{
  "abstract": "Patients with inflammatory bowel disease (IBD) remain at increased risk for colorectal cancer and death from colorectal cancer compared with the general population despite improvements in inflammation control with advanced therapies, colonoscopic surveillance and reductions in environmental risk factors. This guideline update from 2010 for colorectal surveillance of patients over 16 years with colonic inflammatory bowel disease was developed by stakeholders representing UK physicians, endoscopists, surgeons, specialist nurses and patients with GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodological support.An a priori protocol was published describing the approach to three levels of statement: GRADE recommendations, good practice statements or expert opinion statements. A systematic review of 7599 publications, with appraisal and GRADE analysis of trials and network meta-analysis, where appropriate, was performed. Risk thresholding guided GRADE judgements.We made 73 statements for the delivery of an IBD colorectal surveillance service, including outcome standards for service and endoscopist audit, and the importance of shared decision-making with patients.Core areas include: risk of colorectal cancer, IBD-related post-colonoscopy colorectal cancer; service organisation and supporting patient concordance; starting and stopping surveillance, who should or should not receive surveillance; risk stratification, including web-based multivariate risk calculation of surveillance intervals; colonoscopic modalities, bowel preparation, biomarkers and artificial intelligence aided detection; chemoprevention; the role of non-conventional dysplasia, serrated lesions and non-targeted biopsies; management of dysplasia, both endoscopic and surgical, and the structure and role of the multidisciplinary team in IBD dysplasia management; training in IBD colonoscopic surveillance, sustainability (green endoscopy), cost-effectiveness and patient experience. Sixteen research priorities are suggested.",
  "authors": [
    {
      "affiliations": [
        "Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK"
      ],
      "name": "James Edward East"
    },
    {
      "affiliations": [
        "School of Medicine, University of Central Lancashire, Preston, UK"
      ],
      "name": "Morris Gordon"
    },
    {
      "affiliations": [
        "Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK"
      ],
      "name": "Gaurav Bhaskar Nigam"
    },
    {
      "affiliations": [
        "School of Medicine, University of Central Lancashire, Preston, UK"
      ],
      "name": "Vassiliki Sinopoulou"
    },
    {
      "affiliations": [
        "Department of Cellular Pathology, University Hospital Southampton NHS Foundation Trust, Southampton, Southampton, Hampshire, UK"
      ],
      "name": "Adrian C Bateman"
    },
    {
      "affiliations": [
        "The Edinburgh IBD Unit, Western General Hospital, Edinburgh, UK",
        "Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK"
      ],
      "name": "Shahida Din"
    },
    {
      "affiliations": [
        "APC Microbiome Ireland, College of Medicine and Health, University College Cork, Cork, Ireland"
      ],
      "name": "Marietta Iacucci"
    },
    {
      "affiliations": [
        "Division of Gastrointestinal Services, University College Hospitals NHS Trust, London, UK"
      ],
      "name": "Misha Kabir"
    },
    {
      "affiliations": [
        "Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK",
        "Department of Gastroenterology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK"
      ],
      "name": "Christopher Andrew Lamb"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, St Mark's Hospital and Academic Institute, London, UK",
        "Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK"
      ],
      "name": "Ana Wilson"
    },
    {
      "affiliations": [
        "Gastroenterology Department, Chelsea and Westminster Hospital, London, UK"
      ],
      "name": "Ibrahim Al Bakir"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, Darlington Memorial Hospital, Darlington, Durham, UK",
        "Teesside University, Middlesbrough, UK"
      ],
      "name": "Anjan Dhar"
    },
    {
      "affiliations": [
        "Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK"
      ],
      "name": "Sunil Dolwani"
    },
    {
      "affiliations": [
        "Department of Surgery and Cancer, Imperial College London, London, UK",
        "Department of Colorectal Surgery, St Mark's Hospital and Academic Institute, London, UK"
      ],
      "name": "Omar Faiz"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, St Mark's Hospital and Academic Institute, London, UK",
        "Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK"
      ],
      "name": "Ailsa Hart"
    },
    {
      "affiliations": [
        "King’s Health Partners Institute for Therapeutic Endoscopy, King’s College Hospital NHS Foundation Trust, London, UK"
      ],
      "name": "Bu’Hussain Hayee"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, Airedale NHS Foundation Trust, Keighley, West Yorkshire, UK"
      ],
      "name": "Chris Healey"
    },
    {
      "affiliations": [
        "Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK",
        "Stem Cell Biology Lab, Centre for Human Genetics, University of Oxford, Oxford, UK"
      ],
      "name": "Simon John Leedham"
    },
    {
      "affiliations": [
        "Department of Histopathology, University College London, London, UK"
      ],
      "name": "Marco R Novelli"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK"
      ],
      "name": "Tim Raine"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, University Hospital of North Tees, Stockton-on-Tees, UK"
      ],
      "name": "Matthew D Rutter"
    },
    {
      "affiliations": [
        "Gloucestershire Cellular Pathology Laboratory, Cheltenham General Hospital, Cheltenham, Gloucestershire, UK"
      ],
      "name": "Neil A Shepherd"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, St James’s University Hospital, Leeds, UK",
        "Division of Gastroenterology and Surgical Sciences, Leeds Institute of Medical Research, University of Leeds, Leeds, UK"
      ],
      "name": "Venkataraman Subramanian"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, St Mark's Hospital and Academic Institute, London, UK"
      ],
      "name": "Margaret Vance"
    },
    {
      "affiliations": [
        "Crohn’s and Colitis UK, Hatfield, UK"
      ],
      "name": "Ruth Wakeman"
    },
    {
      "affiliations": [
        "Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK"
      ],
      "name": "Lydia White"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, Sandwell and West Birmingham NHS Trust, West Bromwich, UK",
        "Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK"
      ],
      "name": "Nigel J Trudgill"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, Glasgow Royal Infirmary, Glasgow, UK"
      ],
      "name": "A John Morris"
    }
  ],
  "title": "British Society of Gastroenterology guidelines on colorectal surveillance in inflammatory bowel disease",
  "uid": "6d5de905-2c01-5247-b31e-bc5db8af34ee"
}