{
  "abstract": "The hepatic capacity for regeneration is the basis of extended liver surgery allowing resection of up to 70% of liver volume. In cases of insufficient expected future liver remnant (FLR) volumetric optimisation, optimisation can be applied to shift patients from palliation to potentially curative surgical treatment options. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS), a procedure allowing for augmented liver regeneration, has gained specific interest. This two-step surgical intervention, combining portal vein ligation and parenchymal transection, followed by resection after FLR regeneration, expands resectability in patients with extensive tumour burden without compromising oncological outcomes (figure 1A).",
  "authors": [
    {
      "affiliations": [
        "Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic Rochester, Rochester, Minnesota, USA",
        "Department of General Surgery, Medical University of Vienna, Vienna, Austria"
      ],
      "name": "David Pereyra"
    },
    {
      "affiliations": [
        "Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic Rochester, Rochester, Minnesota, USA",
        "Department of Surgery, Clinic Favoriten and Sigmund Freud Private University, Vienna, Austria"
      ],
      "name": "Yawen Dong"
    },
    {
      "affiliations": [
        "Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic Rochester, Rochester, Minnesota, USA",
        "Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Vienna, Austria"
      ],
      "name": "Patrick Starlinger"
    }
  ],
  "title": "Just right: neutrophils exemplify the Goldilocks principle in liver regeneration",
  "uid": "a9231030-c961-563e-8f2b-ca75f85027d6"
}