{
  "abstract": "A recent study by Erkert et al identified a new role for Alzheimer’s disease (AD)-associated presenilins as key molecules involved in maintaining intestinal epithelial function, barrier integrity and immune homeostasis, linking AD and inflammatory bowel disease (IBD) at the molecular level.1 2 Meanwhile, Zhang et al, from an epidemiological perspective, reported that individuals with IBD have a higher risk of developing dementia, particularly AD.3 The ‘gut-brain axis’, which links the intestine and the central nervous system (CNS), has received significant attention in recent years.",
  "authors": [
    {
      "affiliations": [
        "Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden"
      ],
      "name": "Minjia Mo"
    },
    {
      "affiliations": [
        "Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden"
      ],
      "name": "Jiangwei Sun"
    },
    {
      "affiliations": [
        "Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden"
      ],
      "name": "Iris Mikulic"
    },
    {
      "affiliations": [
        "Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden",
        "Department of Paediatrics, Örebro University Hospital, Örebro, Sweden"
      ],
      "name": "Jonas F Ludvigsson"
    },
    {
      "affiliations": [
        "Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden",
        "Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden"
      ],
      "name": "Sara Garcia-Ptacek"
    },
    {
      "affiliations": [
        "Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden",
        "Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden"
      ],
      "name": "Maria Eriksdotter"
    },
    {
      "affiliations": [
        "Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden"
      ],
      "name": "Hong Xu"
    }
  ],
  "title": "Inflammatory bowel disease linked to accelerated cognitive decline in individuals with dementia: a nationwide cohort study",
  "uid": "d73981e1-c130-5122-9ee9-58431574d2d6"
}