{
  "abstract": "It is now widely recognised that host–microbiome interactions play a major role in the control of energy metabolism and insulin sensitivity. Obesity and type 2 diabetes (T2D) are characterised by major shifts in the gut microbiota composition, reduced gut barrier integrity, metabolic inflammation and insulin resistance.1 2 Obesity is associated with increased intestinal permeability and translocation of bacterial fragments as well as intact bacteria to insulin-target tissues such as liver and fat.3 4 However, the underlying mechanisms linking specific taxa and microbiome-derived metabolites to systemic insulin resistance and metabolic alterations in target tissues still remain elusive.",
  "authors": [
    {
      "affiliations": [
        "Institute of Nutrition and Functional Foods, Laval University, Quebec, Canada",
        "Department of Medicine and IUCPQ, Laval University, Quebec, Quebec, Canada"
      ],
      "name": "Andre Marette"
    },
    {
      "affiliations": [
        "Institute of Nutrition and Functional Foods, Laval University, Quebec, Canada"
      ],
      "name": "Genevieve Pilon"
    }
  ],
  "title": "Host–microbiome determinants of insulin resistance in obesity: alone we go faster, together we go further!",
  "uid": "732ed4fb-d9c9-5a7f-9bcf-8bf20d2c04d4"
}