{
  "abstract": "We read with great interest about the recent publication by Trebicka et al in Gut,1 in which the authors developed and validated the Chronic Liver Failure-Systemic Inflammation Gene score (CLIF-SIG) score to predict short-term outcomes in patients with acutely decompensated cirrhosis (AD). The study demonstrated the robustness of CLIF-SIG across multiple international cohorts, predominantly consisting of alcohol-related cirrhosis.",
  "authors": [
    {
      "affiliations": [
        "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center, Department of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"
      ],
      "name": "Jiyang Chen"
    },
    {
      "affiliations": [
        "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center, Department of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"
      ],
      "name": "Xianbin Xu"
    },
    {
      "affiliations": [
        "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center, Department of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"
      ],
      "name": "Sisi Yang"
    },
    {
      "affiliations": [
        "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center, Department of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"
      ],
      "name": "Xia Yu"
    },
    {
      "affiliations": [
        "European Foundation for the Study of Chronic Liver Failure (EF CLIF), Barcelona, Spain",
        "Department of Biomedical Sciences, University of Barcelona, Barcelona, Spain"
      ],
      "name": "Ferran Aguilar"
    },
    {
      "affiliations": [
        "European Foundation for the Study of Chronic Liver Failure (EF CLIF), Barcelona, Spain",
        "Department of Biomedical Sciences, University of Barcelona, Barcelona, Spain",
        "Biochemistry and Molecular Genetics Service, Hospital Clinic of Barcelona-IDIBAPS, Barcelona, Spain"
      ],
      "name": "Joan Claria"
    },
    {
      "affiliations": [
        "European Foundation for the Study of Chronic Liver Failure (EF CLIF), Barcelona, Spain",
        "Department of Internal Medicine B, University of Münster, Munster, Germany"
      ],
      "name": "Jonel Trebicka"
    },
    {
      "affiliations": [
        "Bioinformatics Platform, CIBER of Hepatic and Digestive Diseases (CIBERehd), Barcelona, Spain"
      ],
      "name": "Juan José Lozano"
    },
    {
      "affiliations": [
        "Department of Internal Medicine B, University of Münster, Munster, Germany"
      ],
      "name": "Julia Sidorova"
    },
    {
      "affiliations": [
        "European Foundation for the Study of Chronic Liver Failure (EF CLIF), Barcelona, Spain",
        "Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy"
      ],
      "name": "Paolo Angeli"
    },
    {
      "affiliations": [
        "European Foundation for the Study of Chronic Liver Failure (EF CLIF), Barcelona, Spain",
        "Department of Gastroenterology, Hospital das Clinicas, University of Sao Paulo School of Medicine, Sao Paulo, Brazil"
      ],
      "name": "Alberto Queiroz Farias"
    },
    {
      "affiliations": [
        "European Foundation for the Study of Chronic Liver Failure (EF CLIF), Barcelona, Spain",
        "INSERM, Université Paris Cité, Centre de Recherche sur l'Inflammation (CRI), Paris, France",
        "Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Beaujon, Service d'Hépatologie, Clichy, France"
      ],
      "name": "Richard Moreau"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China"
      ],
      "name": "Wenyi Gu"
    },
    {
      "affiliations": [
        "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center, Department of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"
      ],
      "name": "Zelu Meng"
    },
    {
      "affiliations": [
        "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center, Department of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"
      ],
      "name": "Ying Nie"
    },
    {
      "affiliations": [
        "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center, Department of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"
      ],
      "name": "Yining Zhang"
    },
    {
      "affiliations": [
        "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center, Department of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"
      ],
      "name": "Xiaohan Qian"
    },
    {
      "affiliations": [
        "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center, Department of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"
      ],
      "name": "Yu Shi"
    },
    {
      "affiliations": [
        "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center, Department of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"
      ],
      "name": "Yida Yang"
    }
  ],
  "title": "Validation of the CLIF-SIG score in patients with HBV-related acutely decompensated cirrhosis",
  "uid": "54c17913-823d-5519-a319-465fbd09f4aa"
}