{
  "abstract": "We read with interest the article by Soundararajan et al, titled ‘Integration of lipidomics with targeted, single cell, and spatial transcriptomics defines an unresolved pro-inflammatory state in colon cancer’ published in Gut.1 The study presents a comprehensive analysis of lipid dysregulation in colorectal cancer (CRC), highlighting a pro-inflammatory lipidomic profile and defective lipid class switching. While the integration of multiomics data is commendable, we raise critical concerns about the study’s methodology, interpretation and translational relevance.",
  "authors": [
    {
      "affiliations": [
        "Department of General Surgery, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, Liaoning, People's Republic of China",
        "Liaoning Provincial Key Laboratory of Precision Medicine for Malignant Tumors, Shenyang, Liaoning, People's Republic of China"
      ],
      "name": "Xudong Zhu"
    }
  ],
  "title": "Revisiting lipid dysregulation in colorectal cancer: critical appraisal of pro-inflammatory bias and therapeutic implications",
  "uid": "a909373a-de8b-5b66-b37f-e5f9b3a26eff"
}