{
  "abstract": "The strategy of discarding diminutive colonic polyps (≤5 mm) has been discussed for many years. However, despite their exceedingly low risk of malignancy, implementation has remained limited, with minimal impact on clinical practice. More recently, computer-assisted optical diagnosis (CADx) has been introduced to support and potentially enable broader adoption of this approach. We prospectively assessed patient acceptance and examiner-based quality control in 95 out of 102 patients (93.1%) who consented to this approach, involving a total of 149 polyps. Of these, 143 polyps were reviewed by three examiners blinded to CADx diagnoses and the results were compared with CADx diagnoses. Resect-and-discard accuracy was 83.5% excluding sessile serrated lesions (SSLs), while treating SSLs as neoplastic or hyperplastic yielded 75.9% and 84.3%, respectively. Excluding SSLs, the diagnose-and-leave negative predictive value was 92.3%. Surveillance interval recommendations based on CADx and expert review, aligned with current guidelines, achieved 100% concordance, ensuring appropriate follow-up.",
  "authors": [
    {
      "affiliations": [
        "University of Montreal Hospital Center (CHUM), Montreal, Quebec, Canada"
      ],
      "name": "Mahsa Taghiakbari"
    },
    {
      "affiliations": [
        "Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA"
      ],
      "name": "Douglas K Rex"
    },
    {
      "affiliations": [
        "Gastroenterology and Hepatology, White River Junction VA Medical Center, White River Junction, Vermont, USA"
      ],
      "name": "Heiko Pohl"
    },
    {
      "affiliations": [
        "Gastroenterology and Endoscopy Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy"
      ],
      "name": "Cesare Hassan"
    },
    {
      "affiliations": [
        "University of Montreal Hospital Center (CHUM), Montreal, Quebec, Canada"
      ],
      "name": "Roupen Djinbachian"
    },
    {
      "affiliations": [
        "University of Montreal Hospital Research Center, Montreal, Quebec, Canada"
      ],
      "name": "Felix Huang"
    },
    {
      "affiliations": [
        "University of Montreal Hospital Center (CHUM), Montreal, Quebec, Canada",
        "University of Montreal Hospital Research Center, Montreal, Quebec, Canada"
      ],
      "name": "Daniel von Renteln"
    }
  ],
  "title": "Implementing discard strategies for diminutive polyps using autonomous CADx in clinical practice",
  "uid": "12e64ea8-18ee-56ca-b8e0-bc398cadf2b7"
}