{
  "abstract": "‌Objective To analyse trends in mental and substance use disorders among Asian children aged 5–14 years, identify key risk factors (eg, bullying, abuse, lead exposure) and compare gender/age disparities using Global Burden of Disease (GBD) 2021 data.‌Design Cross-sectional analysis of the GBD 2021 database, focusing on prevalence, disability-adjusted life years (DALYs) and risk factor associations.‌Setting Population-based study across Asian countries, examining the burdens of mental health, especially substance use disorders in high-prevalence regions.‌Participants Children aged 5–14 years in Asia, with gender-stratified subgroups (boys vs girls).‌Result Anxiety, conduct disorders and autism were primary contributors to mental health burdens. Substance use disorders, though less prevalent, rose notably among boys. Girls showed higher burdens of anxiety/depressive disorders. Bullying and childhood abuse were strongly linked to these conditions. Gender disparities in DALYs highlighted boys’ vulnerability to substance use and girls to internalising disorders.‌Conclusion Urgent, region-specific interventions are needed to address bullying, lead exposure and abuse, with gender-sensitive strategies. The study calls for targeted research and policies to mitigate rising mental health challenges in Asian children.",
  "authors": [
    {
      "affiliations": [
        "Clinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China"
      ],
      "name": "Yanyan Wang"
    },
    {
      "affiliations": [
        "Clinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China"
      ],
      "name": "Huifang Yang"
    },
    {
      "affiliations": [
        "Clinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China"
      ],
      "name": "Yizhen Wu"
    },
    {
      "affiliations": [
        "Clinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China"
      ],
      "name": "Jiahui Li"
    },
    {
      "affiliations": [
        "Clinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China"
      ],
      "name": "Chikyu Tsin"
    },
    {
      "affiliations": [
        "Clinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China"
      ],
      "name": "Shuyang Ren"
    },
    {
      "affiliations": [
        "Gongli Hospital, Pudong New Area, Shanghai, China"
      ],
      "name": "Jun Zhang"
    },
    {
      "affiliations": [
        "The New Bund School Attached to No.2 High School of ECNU, Shanghai, China"
      ],
      "name": "Yuling Qiao"
    },
    {
      "affiliations": [
        "Clinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China"
      ],
      "name": "Xiwang Fan"
    }
  ],
  "title": "Burden and risk factors of mental and substance use disorders among children aged 5–14 in Asia from 1990 to 2021: results from the Global Burden of Disease study",
  "uid": "340df865-2724-5ed9-b402-96fa2db2d0fe"
}