{
  "abstract": "The prevalence and burden of metabolic dysfunction-associated steatotic liver disease (MASLD) is very high globally, especially in socially deprived areas. This trend parallels the increasing incidence of type 2 diabetes mellitus and obesity. While MASLD is influenced by multiple factors, including genetics, metabolism and the environment, key modifiable contributors include nutrition, sedentary behaviour, physical activity and sleep quality. The widespread shift towards consumption of ultra-processed food highlights growing concerns around food insecurity and nutritional quality. This review, produced by a multinational team, focuses primarily on the role of nutrition in the prevention and management of MASLD. While physical activity remains a vital component of lifestyle modification, the central emphasis of this review is placed on dietary factors. In this study, we summarise recommendations made by international clinical practice guidelines and highlight the important role that both macronutrients and micronutrients play in liver health. We also evaluate five major dietary patterns in the context of MASLD, outlining the benefits and limitations of each to best support evidence-based patient counselling. We emphasise the importance of personalised and culturally sensitive nutritional advice. Practical tools are provided, including a nutrient-focused summary of beneficial foods and culturally adaptable Mediterranean diet modifications suitable for South and Southeast Asian, African and socioeconomically disadvantaged populations. A sample menu is included to support implementation of the tools in diverse clinical settings.",
  "authors": [
    {
      "affiliations": [
        "Liver Unit, St James’s University Hospital, Leeds, UK",
        "University of Leeds Leeds Institute of Medical Research, Leeds, UK"
      ],
      "name": "Katrina Pekarska"
    },
    {
      "affiliations": [
        "Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK"
      ],
      "name": "Paul N Brennan"
    },
    {
      "affiliations": [
        "Barcelona Institute for Global Health, Barcelona, Spain"
      ],
      "name": "Dana Ivancovsky Wajcman"
    },
    {
      "affiliations": [
        "Department of Dietetics, Queen Elizabeth Hospital Birmingham, Birmingham, Birmingham, UK"
      ],
      "name": "Jennifer Towey"
    },
    {
      "affiliations": [
        "Centre for Immunobiology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK"
      ],
      "name": "Leah Cox"
    },
    {
      "affiliations": [
        "Nutrition and Dietetics, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK"
      ],
      "name": "Katie Weatherby"
    },
    {
      "affiliations": [
        "Newcastle University, Newcastle upon Tyne, UK",
        "Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK"
      ],
      "name": "Stuart McPherson"
    },
    {
      "affiliations": [
        "Division of Gastroenterology and Hepatology, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA"
      ],
      "name": "Jonathan Stine"
    },
    {
      "affiliations": [
        "Liver Patients International, Brussels, Belgium"
      ],
      "name": "Jose Willemse"
    },
    {
      "affiliations": [
        "Barts Liver Centre, Queen Mary University of London, Barts and The London School of Medicine and Dentistry Blizard Institute, London, London, UK"
      ],
      "name": "Wenhao Li"
    },
    {
      "affiliations": [
        "Barts Liver Centre, Queen Mary University of London, Barts and The London School of Medicine and Dentistry Blizard Institute, London, London, UK"
      ],
      "name": "William Alazawi"
    },
    {
      "affiliations": [
        "Barcelona Institute for Global Health, Barcelona, Spain",
        "Graduate School of Public Health and Healthy Policy, CUNY, New York, New York, USA"
      ],
      "name": "Jeffrey V Lazarus"
    },
    {
      "affiliations": [
        "Liver Unit, St James’s University Hospital, Leeds, UK",
        "University of Leeds Leeds Institute of Medical Research, Leeds, UK"
      ],
      "name": "Richard Parker"
    }
  ],
  "title": "Nutrition in MASLD: a patient focused, evidence-based clinician’s guide",
  "uid": "ec651276-fb52-554d-9c8e-ab2de9e44c56"
}