{
  "abstract": "Objective Currently, retinopathy of prematurity (ROP) screening requires a full retinal examination. To reduce the screening burden, we assessed whether a single optic nerve-centred image could detect treatment-requiring ROP. The objective is to investigate the use of a single image centred around the optic disc to detect treatment-requiring ROP, to reduce the burden of ROP screening with the same security of a full retinal examination.Design Retrospective case series.Setting Tertiary referral centre.Population Premature infants screened for ROP in a tertiary referral centre.Main outcome Vascular dilation and tortuosity on a scale from 1 to 5 were blindly labelled by three independent ROP experts using a 8 by 8 mm optic nerve-centred images. Images were automatically generated from images of the routine screening examinations.Results A total of 278 patients (556 eyes) with a mean gestational age of 28.4±2.0 weeks and a mean birth weight of 1059.7±324.0 g were included. Treatment was needed in 49 eyes (8.8%) of 25 patients. A total of 1510 image sets centred on the optic disc were obtained and analysed. When the cut-off of the vascular dilatation and tortuosity rating was fixed at 3 (equivalent to a severe preplus disease), sensitivity and specificity for the detection of prethreshold type 1 ROP were 100% and 88.9%, respectively.Conclusions ROP screening using a single posterior pole image could reduce stress in premature infants without degrading the quality of screening, compare to iterative dilated complete fundus examination.",
  "authors": [
    {
      "affiliations": [
        "Pediatric Ophthalmology Department, Fondation Ophtalmologique Adolphe de Rothschild, Paris, Île-de-France, France"
      ],
      "name": "Yse Borella"
    },
    {
      "affiliations": [
        "Pediatric Ophthalmology Department, Fondation Ophtalmologique Adolphe de Rothschild, Paris, Île-de-France, France",
        "U1153 Epopé, CRESS, Paris, Île-de-France, France"
      ],
      "name": "Thibaut Chapron"
    },
    {
      "affiliations": [
        "Pediatric Ophthalmology Department, Fondation Ophtalmologique Adolphe de Rothschild, Paris, Île-de-France, France"
      ],
      "name": "Florence Metge"
    },
    {
      "affiliations": [
        "Pediatric Ophthalmology Department, Fondation Ophtalmologique Adolphe de Rothschild, Paris, Île-de-France, France"
      ],
      "name": "Youssef Abdelmassih"
    },
    {
      "affiliations": [
        "Pediatric Ophthalmology Department, Fondation Ophtalmologique Adolphe de Rothschild, Paris, Île-de-France, France"
      ],
      "name": "Lucile Senicourt"
    },
    {
      "affiliations": [
        "Pediatric Ophthalmology Department, Fondation Ophtalmologique Adolphe de Rothschild, Paris, Île-de-France, France"
      ],
      "name": "Amandine Barjol"
    },
    {
      "affiliations": [
        "Pediatric Ophthalmology Department, Fondation Ophtalmologique Adolphe de Rothschild, Paris, Île-de-France, France"
      ],
      "name": "Georges Caputo"
    }
  ],
  "title": "Screening of at-risk ROP patients: use of a single small field image centred on the optic disc",
  "uid": "a6403b0c-85ed-58de-a386-fbf4c6f2f533"
}