{
  "abstract": "Objective The James Lind Alliance (JLA) Most Premature Babies Priority Setting Partnership aimed to identify the most important areas for research for infants born <25 weeks’ gestation.Design Employing standardised JLA methodology, questions for research were sought from stakeholders via an online survey. Summary questions were formed and checked against existing evidence, with unanswered questions compiled into a second shortlisting survey for prioritisation by stakeholders. A stakeholder consensus workshop was held to determine the top 10 research priorities.Participants People with lived experience of neonatal intensive care, including parents/carers of preterm infants and adults born preterm, and healthcare professionals caring for preterm infants across Australia, New Zealand and the UK.Main outcome measure The top 10 research priorities for infants born <25 weeks’ gestation.Results From 844 questions received from the initial survey, 81 summary questions were formed, of which 80 were unanswered and included in the second shortlisting survey. The 19 top-ranked questions were taken to the final prioritisation workshop, where the top 10 research priorities were determined by people with lived experience and healthcare professionals. The most important research question identified was ‘What can be done in the neonatal intensive care unit to improve long-term health and developmental outcomes?’. Other important areas for research included antenatal interventions and neonatal care at birth, preventing intraventricular haemorrhages, managing pain, postnatal corticosteroid treatment and supporting families.Conclusions This study identified the most important areas of research for infants born <25 weeks’ gestation, as determined jointly by stakeholders. These findings should be used to guide future research and funding aimed at improving meaningful outcomes for these infants and their families.",
  "authors": [
    {
      "affiliations": [
        "Newborn Research Department, The Royal Women’s Hospital, Melbourne, Victoria, Australia",
        "Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Victoria, Australia",
        "Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Victoria, Australia"
      ],
      "name": "Stacey Peart"
    },
    {
      "affiliations": [
        "Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK"
      ],
      "name": "Olivia Ray"
    },
    {
      "affiliations": [
        "Murdoch Children’s Research Institute, Melbourne, Victoria, Australia"
      ],
      "name": "Laura Galletta"
    },
    {
      "affiliations": [
        "Consumer Advisory Group, Murdoch Children’s Research Institute Centre of Research Excellence in Newborn Medicine, Melbourne, Victoria, Australia"
      ],
      "name": "Amber Bates"
    },
    {
      "affiliations": [
        "Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Victoria, Australia",
        "Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Victoria, Australia"
      ],
      "name": "Rosemarie Anne Boland"
    },
    {
      "affiliations": [
        "Newborn Research Department, The Royal Women’s Hospital, Melbourne, Victoria, Australia",
        "Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Victoria, Australia",
        "Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Victoria, Australia"
      ],
      "name": "Peter G Davis"
    },
    {
      "affiliations": [
        "Academic Neonatal Medicine, Imperial College London, London, UK",
        "Centre for Paediatrics and Child Health, Imperial College London, London, UK"
      ],
      "name": "Chris Gale"
    },
    {
      "affiliations": [
        "Department of Population Health Sciences, University of Leicester, Leicester, UK"
      ],
      "name": "Samantha Johnson"
    },
    {
      "affiliations": [
        "James Lind Alliance, National Institute for Health and Care Research, Evaluation Trials and Studies Coordinating Centre, Southampton, UK"
      ],
      "name": "Suzannah Kinsella"
    },
    {
      "affiliations": [
        "National Perinatal Epidemiological Unit, Clinical Trials Unit, Oxford Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Marian Knight"
    },
    {
      "affiliations": [
        "Newborn Research Department, The Royal Women’s Hospital, Melbourne, Victoria, Australia",
        "Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Victoria, Australia",
        "Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Victoria, Australia"
      ],
      "name": "Louise S Owen"
    },
    {
      "affiliations": [
        "Consumer Advisory Group, Murdoch Children’s Research Institute Centre of Research Excellence in Newborn Medicine, Melbourne, Victoria, Australia"
      ],
      "name": "Louise Pallot"
    },
    {
      "affiliations": [
        "Neonatal Services, Royal Children’s Hospital, Melbourne, Victoria, Australia",
        "Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia"
      ],
      "name": "Trisha M Prentice"
    },
    {
      "affiliations": [
        "not applicable, Oxford, UK"
      ],
      "name": "Patricia Santhanadass"
    },
    {
      "affiliations": [
        "National Perinatal Epidemiological Unit, Clinical Trials Unit, Oxford Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Kayleigh Stanbury"
    },
    {
      "affiliations": [
        "Murdoch Children’s Research Institute, Melbourne, Victoria, Australia",
        "Neonatal Services, Royal Children’s Hospital, Melbourne, Victoria, Australia"
      ],
      "name": "David Tingay"
    },
    {
      "affiliations": [
        "Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Victoria, Australia",
        "Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Victoria, Australia",
        "Department of Maternal Fetal Medicine, The Royal Women's Hospital, Melbourne, Victoria, Australia"
      ],
      "name": "Clare L Whitehead"
    },
    {
      "affiliations": [
        "Newborn Research Department, The Royal Women’s Hospital, Melbourne, Victoria, Australia",
        "Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Victoria, Australia",
        "Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Victoria, Australia"
      ],
      "name": "Brett James Manley"
    },
    {
      "affiliations": [
        "National Perinatal Epidemiological Unit, Clinical Trials Unit, Oxford Population Health, University of Oxford, Oxford, UK",
        "Faculty of Health Sciences, University of Bristol, Bristol, UK",
        "Newborn Services, Southmead Hospital, Bristol, UK"
      ],
      "name": "Charles C Roehr"
    },
    {
      "affiliations": [
        "National Perinatal Epidemiological Unit, Clinical Trials Unit, Oxford Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Pollyanna Hardy"
    },
    {
      "affiliations": [],
      "name": "Steering Group"
    }
  ],
  "title": "Research priorities for the most premature babies born <25 weeks’ gestation: results of an international priority setting partnership",
  "uid": "8f1fc4e3-65d8-53a6-95bf-fe3e49a9c878"
}