{
  "abstract": "Nitazenes are potent synthetic opioids, never licensed for human use due to profound central nervous system and respiratory depression. Developed in the 1950s, they re-emerged in illicit drug supplies in 2019.1 2 Geopolitical events constraining European heroin supply are expected to drive demand for replacements.3 Nitazenes may require higher and repeated naloxone dosing for reversal and have been increasingly identified in postmortem reports, thus representing a public health concern.4 5 Scottish drug-related deaths are the highest in Europe.6 A Surveillance Study of Illicit Substance Toxicity (ASSIST) commenced in 2022 to provide ED surveillance data on illicit drug-related morbidity and mortality, compare clinical characteristics to toxicological analysis and identify emerging trends.",
  "authors": [
    {
      "affiliations": [
        "Emergency Department, QEUH, Glasgow, UK"
      ],
      "name": "Rufus Turner"
    },
    {
      "affiliations": [
        "Emergency Department, QEUH, Glasgow, UK"
      ],
      "name": "Lisa Christine Dunlop"
    },
    {
      "affiliations": [
        "Emergency Department, QEUH, Glasgow, UK",
        "Institute for Health and Wellbeing, University of Glasgow, Glasgow, UK"
      ],
      "name": "David John Lowe"
    },
    {
      "affiliations": [
        "Emergency Department, QEUH, Glasgow, UK"
      ],
      "name": "Fraser Norman"
    },
    {
      "affiliations": [
        "Drugs Team, Public Health Scotland, Edinburgh, UK"
      ],
      "name": "Vicki Craik"
    },
    {
      "affiliations": [
        "Drugs Team, Public Health Scotland, Edinburgh, UK"
      ],
      "name": "Nicole Jarvie"
    },
    {
      "affiliations": [
        "LGC Limited Sport & Specialised Analytical Services, Fordham, UK"
      ],
      "name": "Simon Hudson"
    },
    {
      "affiliations": [
        "University of Glasgow, Glasgow, UK"
      ],
      "name": "Matthew Walters"
    },
    {
      "affiliations": [
        "National Poisons Information Service, Edinburgh, UK"
      ],
      "name": "James Dear"
    },
    {
      "affiliations": [
        "ScotSTAR, Paisley, UK"
      ],
      "name": "Ryan McHenry"
    }
  ],
  "title": "Nitazene detections and clinical characteristics: data from a prospective observational study in a Glasgow emergency department",
  "uid": "c39c377a-e19e-5317-8026-946067982093"
}