{
  "abstract": "Background and Importance Patients undergoing allogeneic haematopoietic stem cell transplantation (allo-HSCT) may experience post-chemotherapy mucositis and are at risk of protein-calorie malnutrition, thus requiring parenteral nutrition (PN). Scientific evidence in surgical patients suggests that early administration of PN tends to reduce hospital stay.Aim and Objectives To analyse whether early initiation of parenteral nutrition influences the duration of hospital stay in patients undergoing allo-HSCT.Material and Methods An observational, analytical, ambispective study was conducted in the Pharmacy Department of a reference General Hospital from January 2023 to September 2025. Patients undergoing allo-HSCT and receiving PN were included. The following variables were recorded: demographic and anthropometric data, admission and discharge dates, date of haematopoietic stem cell infusion, start and end day of PN, and serum prealbumin measurements. Patients were divided into two groups: those who started PN within the first week post-infusion (early-PN) and those who started after one week (delayed-PN). The median and interquartile range (IQR) of hospitalisation days for both groups were calculated and statistical significance was analysed using the Mann–Whitney U test (SPSS v28).Results A total of 47 patients were enrolled in the study. In the early-PN group, 25 patients (72.0% male) were included, with a median age of 59 years (14–70), a mean BMI of 25.5 kg/m 2 ± 3.6 and a mean prealbumin level of 15 mg/dl ± 5. In the delayed-PN group, 22 patients (52.6% male) were included, with a median age of 61 years (24–69), a mean BMI of 23.7 kg/m2 ± 5.5 and a mean prealbumin level of 15 mg/dl ± 5. The median hospital stay in the early-PN group was 34 ± 13 days and in the delayed-PN group 33 ± 4 days, with no statistically significant differences (p = 0.74).Conclusion and Relevance In this limited cohort, early initiation of parenteral nutrition in patients undergoing allogeneic haematopoietic stem cell transplantation wouldn’t appear to influence the duration of hospital stay.Conflict of Interest No conflict of interest",
  "authors": [
    {
      "affiliations": [
        "Hospital Universitario De Salamanca, Servicio De Farmacia, Salamanca, Spain"
      ],
      "name": "N Roso Jiménez"
    },
    {
      "affiliations": [
        "Hospital Universitario De Salamanca, Servicio De Farmacia, Salamanca, Spain"
      ],
      "name": "M López Álvarez"
    },
    {
      "affiliations": [
        "Hospital Universitario De Salamanca, Servicio De Hematología Y Hemoterapia, Salamanca, Spain"
      ],
      "name": "I Perales Cia"
    },
    {
      "affiliations": [
        "Hospital Universitario De Salamanca, Servicio De Endocrinología Y Nutrición, Salamanca, Spain"
      ],
      "name": "C Romera Pérez"
    },
    {
      "affiliations": [
        "Hospital Universitario De Salamanca, Servicio De Farmacia, Salamanca, Spain"
      ],
      "name": "L Lorenzo Vidal"
    },
    {
      "affiliations": [
        "Hospital Universitario De Salamanca, Servicio De Farmacia, Salamanca, Spain"
      ],
      "name": "I García Paris"
    },
    {
      "affiliations": [
        "Hospital Universitario De Salamanca, Servicio De Farmacia, Salamanca, Spain"
      ],
      "name": "R Pérez López"
    },
    {
      "affiliations": [
        "Hospital Universitario De Salamanca, Servicio De Farmacia, Salamanca, Spain"
      ],
      "name": "C González Álvarez-Cedrón"
    },
    {
      "affiliations": [
        "Hospital Universitario De Salamanca, Servicio De Farmacia, Salamanca, Spain"
      ],
      "name": "C González Zar"
    },
    {
      "affiliations": [
        "Hospital Universitario De Salamanca, Servicio De Farmacia, Salamanca, Spain"
      ],
      "name": "A Rodríguez Sánchez"
    }
  ],
  "title": "4CPS-190 Duration of hospital stay according to the timing of parenteral nutrition initiation in patients undergoing allogeneic haematopoietic stem cell transplantation",
  "uid": "cfed93de-d98d-56ab-a494-26ebba0cb58b"
}