{
  "abstract": "Background and Importance Oncohematological patients (OHP) often have very low vitamin D(VitD) levels (<20 ng/dL), which is associated with higher morbi-mortality. Many OHPs have a non-functioning gastrointestinal tract due to the toxicity of the treatments they receive, limiting oral absorption and requiring the use of parenteral nutrition(PN). VitD replacement is an added complication due to factors such as bioavailability and route of administration.Aim and Objectives Analyse VitD levels and assess the differences in analytical requests in OHP with PN. Study the frequency and effectiveness of the use of different VitD formulations as restorative treatment.Material and Methods Retrospective observational study of OHP with PN from 2023 to July 2025. Based on medical records and the PN formulation program, the following data were recorded in a database: sex and age, anthropometric parameters, diagnosis, number of days with PN and days elapsed until the request for levels during NP, date and value of all blood VitD levels; evolution and reason for suspension of PN; administration of VitD. Literature review using the keywords, PN, VitD and OHP.Results A total of 177 OHPs with PN were included, as described in table 1. The main indications for PN were related to complications secondary to digestive cancer. The average number of days with PN was 11, and it took 1 day to request levels. Levels were requested in 76% of OHP(12±7 ng/dl), falling within the deficiency range(<20 ng/dl). The most frequent reason for ending PN was progression to oral nutrition(59%). The administration of different VitD formulations was analysed, but their use was negligible.Abstract 5PSQ-019 Table 1Description of patientsConclusion and Relevance The high prevalence of vitamin D deficiency in OHP with PN is evident, highlighting the need to standardise testing and optimise levels through a joint protocol with prescribers. This situation represents a significant clinical burden in the course of the disease and suggests that VitD supplementation through PN could be explored as an additional strategy.Conflict of Interest No conflict of interest",
  "authors": [
    {
      "affiliations": [
        "Hospital Universitario De Jaén, Farmacia Hospitalaria, Jaén, Spain"
      ],
      "name": "JJ Losada Gómez"
    },
    {
      "affiliations": [
        "Hospital Universitario De Jaén, Farmacia Hospitalaria, Jaén, Spain"
      ],
      "name": "J Moreno Banegas"
    },
    {
      "affiliations": [
        "Hospital Universitario De Jaén, Farmacia Hospitalaria, Jaén, Spain"
      ],
      "name": "M Fernandez Mimbrera"
    },
    {
      "affiliations": [
        "Hospital Universitario De Jaén, Farmacia Hospitalaria, Jaén, Spain"
      ],
      "name": "B Morales Rivero"
    }
  ],
  "title": "5PSQ-019 Evaluation and influence of vitamin d levels in oncohematological patients with parenteral nutrition",
  "uid": "7f47efe7-9ecd-590d-bf32-225e781a0297"
}