{
  "abstract": "Background and Importance Safe management of the medication use process is a key priority in hospitals and is subject to specific requirements from Accreditation XXX. Regular audits help identify strengths and areas for improvement in medication preparation and administration practices.Aim and Objectives To assess compliance with medication preparation and administration practices in a mother-child university hospital and identify key areas requiring improvement.Material and Methods This cross-sectional observational study was conducted between April and June 2025 across 21 care units (inpatient wards, intensive care, and outpatient clinics). A total of 42 trained auditors performed 436 direct observations across all work shifts. A standardised 82-item checklist, covering preparation, administration, hygiene, labelling, and documentation, was used including criteria related to hazardous drugs (G1, G2, G3). Each item was rated as compliant, non-compliant, or not applicable. Data were analysed using descriptive statistics and compared with previous audits (Student’s t test and chi-square test, p<0.05).Results Most observed healthcare professionals were nurses (82.5%). Routes of administration were enteral (52.3%) and parenteral (47.7%). Compliance ranged from 37% to 100%, with 75.6% of criteria showing rates ≥75%. The most compliant practices included selecting the correct medication (100%), performing double checks (98%), using smart infusion pump libraries (98%), and verifying the expiration date and integrity of the medication (97%). Recurrent weaknesses included work surface hygiene (37%), communication of adverse effects (44%), hand hygiene after handling hazardous drugs (41%) and validation of patient or parent understanding of the medication (66%). For hazardous drugs (G1–G3), which represented 9% of observations, several critical steps showed low compliance: cleaning of the preparation surface (19%), timely use of personal protective equipment (49%), and use of appropriate preparation areas (72%). Interruptions were absent in 57% of observations but occurred one or more times in 43% of cases.Conclusion and Relevance The audit revealed overall high compliance and consolidation of several practices but highlighted persistent deficiencies. Non-compliance related to hazardous-drug handling, insufficient hand hygiene and work-surface cleaning, frequent interruptions, and limited patient communication should be prioritised in future action plans to further strengthen medication safety and compliance with Accreditation XXX standards.Conflict of Interest No conflict of interest",
  "authors": [
    {
      "affiliations": [
        "Unité De Recherche En Pratique Pharmaceutique- Chu Sainte Justine, Pharmacie, Montréal, Canada"
      ],
      "name": "L Lardeux"
    },
    {
      "affiliations": [
        "Unité De Recherche En Pratique Pharmaceutique- Chu Sainte Justine, Pharmacie, Montréal, Canada"
      ],
      "name": "G Escoffier"
    },
    {
      "affiliations": [
        "Unité De Recherche En Pratique Pharmaceutique- Chu Sainte Justine, Pharmacie, Montréal, Canada"
      ],
      "name": "S Atkinson"
    },
    {
      "affiliations": [
        "Direction Des Soins Infirmiers, CHU Sainte Justine, Montréal, Canada"
      ],
      "name": "S Duval"
    },
    {
      "affiliations": [
        "Direction Des Soins Infirmiers, CHU Sainte Justine, Montréal, Canada"
      ],
      "name": "V Pelchat"
    },
    {
      "affiliations": [
        "Unité De Recherche En Pratique Pharmaceutique- Chu Sainte Justine, Pharmacie, Montréal, Canada",
        "Faculté De Pharmacie, Université De Montréal, Montréal, Canada"
      ],
      "name": "JF Bussières"
    }
  ],
  "title": "5PSQ-137 Audits on medication preparation and administration: a cross-sectional observational study in a mother–child university hospital centre",
  "uid": "7ceb0565-7e59-519a-8017-96c34efb4800"
}