{
  "abstract": "Background and Importance Parenteral administration of drugs is a pivotal part in patient’s hospital journey. Therefore infusion set-up errors can expose patients to adverse clinical complications, especially for those who are in Intensive Care Units (ICU).Aim and Objectives To minimise errors and secure infusion set-up, an analysis of existing practices in ICU will be carried out. Several approaches for improvement will be suggested, as optimising infusion set-up, in accordance to the Infusion Therapy Standards of Practice (ITSP).Material and Methods Over a month, a multidisciplinary team (eg pharmacist, hygiene specialist nurse, ICU nurse) registered data on an pre-established analysis framework with 5 main criteria among which can be found characteristics of the access route (infusion mode, catheter type, insertion site), infusion set-up architecture and therapies administered. Each framework was specific to the intravascular device used. Data were analysed and linked with medical prescriptions from the ICU software.Results 42 patients were audited and had 59 intravascular devices of which 58% of Peripheral Intravenous Catheter (PIV), 30% of Central Venous Catheter (CVC), 10% of MIDlines, 2% of PICClines and 0% of implantable ports with a total of 327 infusion lines (110 main lines (ML), 217 secondary lines (SL)). The ICU has its own infusion set-up protocol for 4-lumen CVC, ensuring unicity. 100% of parenteral nutrition were given in accordance to the ITSP. However, 91% of lines didn’t include a non-return valves (NRV). Afterwards, the analysis of medical charts confirmed the consistency between prescriptions and observed treatments and highlighted 10 drug incompatibilities.Conclusion and Relevance The care of patients in ICU is complex and their clinical conditions can change very quickly. Infusion set-up are replaced at least every 5 days. The absence of NRV is due to absence of this MD in their ward stock. They will be provided soon, along with a training of their management. A table of physical and chemical incompatibilities (IPC) of Y-site injectables was drawn up according to the main therapies used in ICU. As a result of this work, a new infusion protocol for CVC will be created collaboratively by a multidisciplinary team including the ICU team.Conflict of Interest No conflict of interest",
  "authors": [
    {
      "affiliations": [
        "Centre Hosptalier Départemental Vendée, Pharmacie, La Roche Sur Yon, France"
      ],
      "name": "E Salou"
    },
    {
      "affiliations": [
        "Centre Hosptalier Départemental Vendée, Pharmacie, La Roche Sur Yon, France"
      ],
      "name": "A Gillette"
    },
    {
      "affiliations": [
        "Centre Hosptalier Départemental Vendée, Pharmacie, La Roche Sur Yon, France"
      ],
      "name": "C Hurlupé"
    },
    {
      "affiliations": [
        "Centre Hosptalier Départemental Vendée, Uapi, La Roche Sur Yon, France"
      ],
      "name": "A Pouzet"
    },
    {
      "affiliations": [
        "Centre Hosptalier Départemental Vendée, Uapi, La Roche Sur Yon, France"
      ],
      "name": "C Chantereau-Jansen"
    },
    {
      "affiliations": [
        "Centre Hosptalier Départemental Vendée, Médecine Intensive Et Réanimation, La Roche Sur Yon, France"
      ],
      "name": "I Vinatier"
    },
    {
      "affiliations": [
        "Centre Hosptalier Départemental Vendée, Médecine Intensive Et Réanimation, La Roche Sur Yon, France"
      ],
      "name": "JC Lacherade"
    },
    {
      "affiliations": [
        "Centre Hosptalier Départemental Vendée, Pharmacie, La Roche Sur Yon, France"
      ],
      "name": "V Le Bigot"
    }
  ],
  "title": "5PSQ-113 Audit of infusion set-up in intensive care: towards optimisation and safety enhancement",
  "uid": "40b6c522-d66f-5dc8-8f62-b9e754f37f01"
}