{
  "abstract": "Background and Importance The prescription of iron carboxymaltose upon discharge is common in hospitals. It improves adherence and iron bioavailability in patients compared to the oral pharmaceutical form. However, in many cases, follow-up is insufficient, making it challenging to assess its effectiveness.Aim and Objectives Evaluate the efficacy of carboxymaltose iron treatment at hospital discharge and assess the subsequent analytical and clinical follow-up of the patient.Material and Methods Retrospective observational study conducted between January and December 2024, that included inpatients who were administered iron carboxymaltose upon discharge from the hospital. The data collected were: age, sex, hospital readmission, baseline haematological parameters (haemoglobin, iron, ferritin, transferrin) and immediately after administration and treatment with oral iron. Information was obtained from digital medical records (Diraya), Dominion Farma Tools and Modulab. Patients with complete assessments were defined as those for whom baseline and post-treatment analytical values were available.Results Carboxymaltose iron was administered to 85 patients (56.5% men, mean age 70.2 years). Eight patients did not meet inclusion criteria and were excluded.An increase in mean haemoglobin was observed in 89.6% of patients (2.7 g/dL compared to the mean baseline value of 8.8 g/dL) and anaemia was reversed in 29.8% cases. Baseline and final iron data were obtained in 23 patients with a mean increase of 46.3 µg/dL (baseline 31.5 µg/dL, final 77.8 µg/dL). Ferritin increased in 23 patients by an average of 298.9 ng/mL (baseline mean 245 ng/mL, final mean 543.9 ng/mL). Eighteen patients with complete transferrin assessment were observed, with a mean decrease of 38.6 mg/dL (baseline mean 237.5 mg/dL, final mean 198.9 mg/dL). Regarding oral iron, 23 patients had it prescribed prior to admission and 33 after discharge. During the study period, 37 patients were readmitted of whom 10 died, but no interrelation was found.Conclusion and Relevance -Administration of iron carboxymaltose improved haemoglobin and serum iron levels. -In almost two-thirds of patients, the therapeutic goal of reversing anaemia was not achieved, justified by a low baseline haemoglobin level. -Incomplete assessment of iron metabolism hinders optimal analytical monitoring.Conflict of Interest No conflict of interest",
  "authors": [
    {
      "affiliations": [
        "Hospital Universitario Puerto Real, Pharmacy, Puerto Real, Spain"
      ],
      "name": "CL Elena"
    },
    {
      "affiliations": [
        "Hospital Universitario Puerto Real, Pharmacy, Puerto Real, Spain"
      ],
      "name": "CC Manuel"
    },
    {
      "affiliations": [
        "Hospital Universitario Puerto Real, Pharmacy, Puerto Real, Spain"
      ],
      "name": "PB Elisa"
    },
    {
      "affiliations": [
        "Hospital Universitario Puerto Real, Pharmacy, Puerto Real, Spain"
      ],
      "name": "MD Gil-Sierra"
    },
    {
      "affiliations": [
        "Hospital Universitario Puerto Real, Pharmacy, Puerto Real, Spain"
      ],
      "name": "DN Jorge"
    }
  ],
  "title": "4CPS-172 Evaluation of the effectiveness of carboxymaltose iron treatment at hospital discharge",
  "uid": "3ebf117c-bb10-51be-92c9-cfcc11557424"
}