{
  "abstract": "Background and Importance Population growth presents major challenges, particularly the rise in frailty among older adults, which is often associated with multiple chronic diseases and the use of several medications. This situation increases the risk of adverse drug events and interactions.Aim and Objectives The objective of this study is to evaluate the use of dispensed medications in older adults in Catalonia, based on their frailty status.Material and Methods A multicentre, multidisciplinary, and longitudinal (1 year: 2021) study was conducted using retrospective data collection. Data were obtained from Programme for Data Analytics for Research and Innovation (PADRIS), Agency for Health Quality and Assessment of Catalonia (AQuAS). The study included Catalan population aged ≥65 years. The variables were: sociodemographic (age and sex); drug dispensed; and e-SIF criteria (electronic instrument that categorised frailty status in non-frail (robust, pre-frail) and frail (moderately or severely frail).Results The population included 1.564.611 individuals and the number of dispensed packs was 63.866.572. The annual average number of drugs dispensed per person was 6.5 (6.7 women, 6.2 men). In the frail group, the average was 9.8 drugs; while in the non-frail group was 5.7.46.6% of population were dispensed ≥5 drugs/year (48.7% women, 43.8% men). 32.6% of people aged 65–69 were dispensed ≥5 drugs/year, 42.0% between 70–74, 50.6% between 75–79, 57.4% between 80–84, 60.6% between 85–89, 60.2% between 90–94, and 54.9% of people aged ≥95. 39.3% of non-frail (31.1% robust, 68.9% pre-frail) and 84.5% of frail (65.1% moderately frail, 34.9% severely frail) people were dispensed ≥5 drugs/year.14.4% of the population were dispensed ≥10 drugs/year (15.8% women, 12.6% men). 7.1% of people aged 65–69 were dispensed ≥10 drugs/year, 10.9% between 70–74, 15.9% between 75–79, 21.1% between 80–84, 23.6% between 85–89, 22.7% between 90–94, and 17.8% of people aged ≥95. 8.3% of non-frail (14.3% robust, 85.7% pre-frail) and 46.7% of frail (57.6% moderately frail, 42.4% severely frail) people were dispensed ≥10 drugs/year.Conclusion and Relevance Medication use tends to increase with age and is more frequent among individuals with frailty. These findings highlight the importance of conducting regular medication reviews and implementing deprescribing strategies, particularly in frail older adults.Conflict of Interest No conflict of interest",
  "authors": [
    {
      "affiliations": [
        "Hospital Universitari De Mataro, Pharmacy, Mataro, Spain"
      ],
      "name": "L Perez Cordon"
    },
    {
      "affiliations": [
        "Hospital Universitari De Mataro, Pharmacy, Mataro, Spain"
      ],
      "name": "B Garcia Javier"
    },
    {
      "affiliations": [
        "Hospital Universitari De Mataro, Pharmacy, Mataro, Spain"
      ],
      "name": "L Lopez Vinardell"
    },
    {
      "affiliations": [
        "Hospital Universitari De Mataro, Internal Medicine, Mataro, Spain"
      ],
      "name": "M Cabre Roure"
    },
    {
      "affiliations": [
        "Hospital Universitari De Mataro, Pharmacy, Mataro, Spain"
      ],
      "name": "F Sala Piñol"
    },
    {
      "affiliations": [
        "Hospital Universitari De Mataro, Pharmacy, Mataro, Spain"
      ],
      "name": "M Sancho Riba"
    },
    {
      "affiliations": [
        "Hospital Universitari De Mataro, Research Unit, Mataro, Spain"
      ],
      "name": "M Serra-Prat"
    }
  ],
  "title": "4CPS-272 Medication prescribing among the elderly in Catalonia",
  "uid": "2b529f79-17bf-59f1-aaf3-df46084eee95"
}