{
  "abstract": "Introduction Despite being developed nearly 50 years ago, continuous positive applied pressure (CPAP) remains the gold standard treatment for obstructive sleep apnoea (OSA; Cao et al 2017). A major issue with CPAP treatment is the non-adherence rates across hospitals and even countries, sitting between 30-40% since 1994 (Rotenberg, Murariu, Pang 2016). This study investigates whether CPAP 95th percentile pressure levels are correlated with CPAP compliance. The primary hypothesis is that there will be a significant correlation between CPAP pressure and CPAP compliance.Method Data from patients using standard ResMed Airsense 10 & 11 machines (n=198) were compared within group. All machines automatically titrated pressure. Participants with mild, moderate, and severe apnoea were included. Participants were selected from the University College London Hospital (UCLH) Sleep and Snoring department’s AirView account. There was no exclusion criteria based on age, gender or medical history. Treatment efficacy was measured by AHI average over 365 days. Compliancy was measured by the percentage of days CPAP was used >= 4 hours out of days CPAP was used over the last 365 of data as well as minutes used on average per 12-hour session.Results PRELIMARY DATA RESULTS. Pearson’s correlation test was used to investigate if there were any significant correlations. A significant positive statistical correlation was found between CPAP pressure and CPAP compliance with a statistical threshold of p < 0.05 (r(49) = 0.42, p = 0.0039). No significant statistical correlations were found between compliancy percentages and leak levels r(49) = -0.13, p = 0.39). No significant statistical correlations were found between compliancy percentages and untreated apnoea hypopnea index (AHI; r(49) = -0.033, p = 0.83). No significant statistical correlations were found between compliancy percentages and treated AHI (r(49) = -0.20, p = 0.19). Figure 1Conclusions There was a clinically relevant significant correlation between CPAP compliance and 95th percentile pressure levels. Therefore, the null hypothesis can be rejected. Further investigation on internal airway structures that correlate with high CPAP pressures should be undertaken to determine the phenotype of the extra airway support. This can then, perhaps, predict compliance before CPAP administration.Abstract P40 Figure 1",
  "authors": [
    {
      "affiliations": [
        "University College London Hospital, London, United Kingdom"
      ],
      "name": "Zoe Botting"
    }
  ],
  "title": "P40 A clinical investigation into continuous positive airway pressure level and the relationship to continuous positive airway pressure compliance",
  "uid": "1fc96732-853e-5894-a52d-c63421fd397c"
}