{
  "abstract": "Background Treatment of obstructive sleep apnoea (OSA) is aimed at improving symptoms, particularly daytime sleepiness. The Epworth sleepiness score (ESS) is used to assess treatment response, but as a subjective measure is susceptible to the placebo effect. This study estimates the placebo effect of mandibular advancement devices (MAD).Discussion Seven studies were identified that included a sham device and reported pre & post ESS. Active MAD resulted in a 4.2-point improvement in ESS, compared to a 1.8-point improvement with sham devices (table 1). Since sham devices are unlikely to improve nocturnal breathing events, any change in symptoms must result from other mechanisms, such as placebo effect.Abstract P25 Table 1Change in ESS with active and sham MAD",
  "authors": [
    {
      "affiliations": [
        "King’s College Hospital, London, United Kingdom"
      ],
      "name": "Marcus Pittman"
    },
    {
      "affiliations": [
        "Mid & South Essex NHS Trust, Southend-on-Sea, United Kingdom"
      ],
      "name": "Dora Amran"
    }
  ],
  "title": "P25 Placebo effect of mandibular advancement devices",
  "uid": "ef306cbc-ffe9-57e0-b1b8-39cbdf8950e0"
}