{
  "abstract": "Introduction Children with Down syndrome (DS) are at risk of obstructive sleep apnoea (OSA) which can cause complex problems (Hill et al., Sleep Medicine 2016; 27–28: 99–106). Whilst polysomnography (PSG) is recommended to diagnose OSA (Simpson et al., Nature and Science of Sleep 2018; 10: 287–293), home oximetry monitoring can be effective to determine those in urgent need of further testing (Hill et al., Archives of Disease in Childhood 2018; 103: 962 -967). We recently started a routine screening program for this patient group.Methods We screened 64 patients (0.5 – 5 years) with DS using home oximetry monitoring (Masimo Rad 97 Pulse Oximeter, CA, USA) for 2 nights at home annually until the age of 5. The results were downloaded using Visi-download (Oxford, UK) and mean saturations, oxygen desaturation index (ODI), nadir and Delta 12s index were analysed. The reports were then reviewed by a respiratory consultant who determined the next steps.Results 164 studies were performed on 64 individual patients. There was adequate data in 93.8% studies. 36 patients (56.3%) had normal results. 28 patients (43.8%) were found to have abnormal results. 11 (17.2%)of these were referred for PSGs and 14 (21.9%) were referred to a specialist joint Respiratory/ENT clinic for possible tonsillectomy and/or adenoidectomy. 1 (1.6%) patient required immediate admission and set-up on CPAP. Table 1 shows the data from both patients with normal and abnormal results.Abstract P43 Table 1The mean (SD) data from the normal and abnormal groupsConclusion This audit highlights the importance of screening individuals with DS. Our findings show that 43% of patients required further evaluation, despite no specific clinical concern. These results highlight the need for routine screening to enable early intervention to improve patient outcomes and quality of life. Early detection can play a key role in managing health risks associated with DS. Home oximetry is both simple and quick, with shorter wait times than PSG. Although 17% required further PSG testing, this study supports the use of initial screening via home oximetry to prioritise those in urgent need and safely monitor those with lesser symptoms.",
  "authors": [
    {
      "affiliations": [
        "Alder Hey Children’s Hospital, Liverpool, UK"
      ],
      "name": "Laurie Mccartney"
    },
    {
      "affiliations": [
        "Alder Hey Children’s Hospital, Liverpool, UK"
      ],
      "name": "Philip Lawrence"
    },
    {
      "affiliations": [
        "Alder Hey Children’s Hospital, Liverpool, UK"
      ],
      "name": "Ruth Trinick"
    },
    {
      "affiliations": [
        "Alder Hey Children’s Hospital, Liverpool, UK"
      ],
      "name": "Gemma Saint"
    }
  ],
  "title": "P43 Home oximetry screening for sleep disordered breathing in children with down syndrome",
  "uid": "019ef1dd-af98-5893-b063-72f0087f849d"
}