{
  "abstract": "Background Surgical site infections (SSIs) represent a significant source of morbidity during pancreaticoduodenectomy. The use of piperacillin–tazobactam (pip–tazo) has been shown to significantly reduce the incidence of SSI in this patient population. We thus elected to perform a quality improvement (QI) project to reduce superficial and deep SSI rates by ensuring all patients received pip–tazo as antibiotic prophylaxis.Methods We collected baseline retrospective data on a historical cohort of patients undergoing pancreaticoduodenectomy or total pancreatectomy from 1 January 2022 to 31 December 2022. We then launched our QI project on 1 January 2023, consisting of a multidisciplinary team creation and numerous outreach activities. The project had two Plan, Do, Study, Act (PDSA) cycles and ran until April 2024. The Standards for Quality Improvement Reporting Excellence guidelines were used to report results.Results Baseline cohort data included 64 patients, with 32% receiving pip–tazo and 39% developing an SSI. During phase one of our QI project (1 January 2023–31 August 2023), 54 patients underwent surgery, 90.7% received pip–tazo and 27.8% developed an SSI. Those who had undergone preoperative biliary stenting had a higher SSI rate (46.9% vs 4.4%). We thus added a second SSI reduction measure to patients with biliary stents: the ringed wound protector. During the second phase of our QI project (1 September 2023–1 April 2024), 51 patients underwent surgery, 98.0% received pip–tazo and 65.0% had a wound protector placed. SSI rates in this group were 9.8%.Conclusion We describe a QI project whereby we increased the rates of correct antibiotic dosing in patients undergoing pancreatectomy to 98.0%. Although pip–tazo reduced SSI rates, the addition of a ringed wound protector in patients at high risk further reduced rates of SSI. We thus suggest the use of pip–tazo and ringed wound protectors as an effective strategy to reduce SSI rates in patients undergoing pancreatectomy.",
  "authors": [
    {
      "affiliations": [
        "Department of Surgery, Ottawa General Hospital, University of Ottawa, Ottawa, Ontario, Canada",
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Richard W Gilbert"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Michelle Kwon"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Muhammad Uzair Khalid"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Michael Bleszynski"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Stephen W Chung"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Graziano Oldani"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Maja Segedi"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Mitchell Webb"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Philemon Leung"
    },
    {
      "affiliations": [
        "Department of Medicine, Division of Infectious Disease, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Allison Mah"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Megan O’Brien"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Pharmacology and Therapeutics, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Kristen M Kidson"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Stephanie Chartier-Plante"
    },
    {
      "affiliations": [
        "Department of Surgery, Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada"
      ],
      "name": "Peter Kim"
    }
  ],
  "title": "Reducing surgical site infections in patients undergoing pancreatic resection: a quality improvement initiative",
  "uid": "85e6faf1-9d83-54de-9d77-a21f9f2b8afd"
}