{
  "abstract": "Background Developmental disabilities are due to impairment on physical, learning, language or behavioral areas. These conditions have been related to prematurity, low birthweight, maternal complications during pregnancy and congenital malformation. Efforts have been made to improve the neonatal intensive care. While dramatic reduction was seen in the neonatal mortality rates, no improvement seen in the neurodevelopmental outcome of the surviving newborns.Objectives This study determined the neurodevelopmental outcome of high-risk infants one year after their initial evaluation. The socio-demographic, clinical profile, and risk factors associated with adverse neurodevelopmental outcomes were identified.Methods This was an analytical cross-sectional study design that included infants enrolled in our high-risk clinic. Battelle Developmental Inventory-2 Full Evaluation NU was used for developmental assessment. The maternal, perinatal, neonatal, and postnatal factors were collected and analyzed.Results Of the 76 patients included, 52 (68.5%) high risk infants were at par for the age. The overall incidence of developmental delay detected was 31.5% (n=24); 9-with adverse outcome (6-language delay, 2-motor, 1-adaptive), 9-GDD, and 6-Cerebral Palsy. HIE stage 2, secondary generalized epilepsy and combined neonatal factors were found to be significantly associated with developmental delay. Higher proportion of breastfeeding was seen in at par children compared to the infants with delay.Conclusions Adverse neurodevelopmental outcome was seen in high-risk infants who had hypoxic ischemic encephalopathy stage 2, secondary generalized epilepsy and combined neonatal factors. Breastfeeding is a significant protective factor for at par infants. The study provides baseline data for improving existing healthcare practices and reducing the burden of developmental disabilities.",
  "authors": [
    {
      "affiliations": [
        "Section of Developmental and Behavioral Pediatrics, National Children’s Hospital, Quezon City, Metro Manila, Philippines"
      ],
      "name": "Charisse Zuniga Posio"
    },
    {
      "affiliations": [
        "Section of Developmental and Behavioral Pediatrics, National Children’s Hospital, Quezon City, Metro Manila, Philippines"
      ],
      "name": "Florita Yambao-Dela Cruz"
    }
  ],
  "title": "8 Neurodevelopmental outcome of infants one year after initial evaluation at the high-risk clinic of a tertiary hospital in Metro Manila",
  "uid": "d65ea357-7d61-5998-9658-c85dc39f4774"
}