{
  "abstract": "Objectives To describe the impact of the Sentido'S® Model on adaptive behaviors in children aged 3–7 years with autism spectrum disorder and neurodevelopmental challenges in Patagonia, Argentina, evaluating its effectiveness as a manualized intervention contextually appropriate for middle-income countries.Methods Prospective longitudinal study ( NCT06477666) with pretest-posttest design and 17-week follow-up. Participants: 24 children with autism spectrum disorder diagnoses according to DSM-5. Transcomplex intervention integrating Applied Behavior Analysis, Ayres Sensory Integration, and Psychoneuroimmunology, structured across nine bio-neuro-sensory- psycho-social-spiritual-occupational-nutritional-ecological dimensions, six fundamental premises, and three intervention strata (children, caregivers, professionals). Implementation: 14 weeks (4 weekly sessions, 60 minutes) with systematic family inclusion (12 structured sessions). Measures: Vineland-3 (adaptive behaviors), Goal Attainment Scaling (individualized objectives), Family Outcome Survey (family competencies). Analysis: Repeated measures ANOVA with Bonferroni post-hoc comparisons.Results Statistically significant improvements are expected in Vineland-3 ABC composite scores from baseline to follow-up, with maintenance of post-intervention skills and improvements in family competencies. Preliminary results will be available for presentation.Conclusions This model represents a methodological innovation for middle-income countries, providing the first manualized transcomplex framework integrating evidence-based approaches with culturally appropriate principles. Findings will contribute to inclusive public policy development and evidence for effective, replicable programs in resource-limited contexts.",
  "authors": [
    {
      "affiliations": [
        "Instituto Universitario de Ciencias de la Salud - Fundación H. A. Barceló, Caba, Argentina"
      ],
      "name": "Bárbara Muriel Tomás"
    }
  ],
  "title": "222 Sentido'S® model: transcomplex intervention for adaptive behavior acquisition in children with neurodevelopmental challenges in Patagonia, Argentina",
  "uid": "6522f04a-e647-57c9-9397-7bdee9c21d2a"
}