{
  "abstract": "Introduction Dementia is a growing global public health priority, with the WHO Global Action Plan (GAP) calling for coordinated efforts worldwide. Italy, one of the oldest nations globally, faces a significant challenge with approximately 2 million individuals living with dementia or mild cognitive impairment. In response, the Italian Fund for Alzheimer’s and other Dementias (IFAD) was established in 2020 to align national efforts with the WHO GAP’s objectives. This study analyses IFAD activities from 2021 to 2023, offering insights into Italy’s public health response to dementia and its relevance to global strategies.Methods We conducted a structured, iterative review of all activities coordinated by the Italian Dementia Observatory (OssDem-Istituto Superiore di Sanità (ISS)) within IFAD 2021–2023. Global, regional and national documents on dementia prevention, care and support were retrieved from official websites, institutional repositories and targeted web searches using the keywords ‘dementia’, ‘brain health’ and ‘ageing’. Two reviewers independently screened and extracted data with a predefined matrix mapped to the seven WHO GAP Action Areas. Human-subject studies cited had independent ethics approval and informed consent; no new data were collected for this review.Results IFAD activities led to substantial progress in dementia care services, with memory clinics, residential care facilities and daycare centres mapped, revealing regional disparities in service provision. Modifiable risk factors accounted for 39.5% of dementia cases in Italy, with an estimated 67 000 cases preventable through risk reduction. National guidelines were developed to standardise dementia care pathways, and training programmes addressed gaps in HP and caregiver preparedness, particularly highlighted by the COVID-19 pandemic.Discussion Italy’s experience provides valuable lessons for countries facing similar demographic challenges. The IFAD extension to 2024–2026 aims to address persistent regional disparities and further implement national guidelines and prevention strategies. By integrating Italy’s progress with broader international frameworks, the Italian model can inform global efforts to enhance dementia care, highlighting the importance of scalable, regionally adapted strategies for addressing the growing global burden of dementia.",
  "authors": [
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Antonio Ancidoni"
    },
    {
      "affiliations": [
        "Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy"
      ],
      "name": "Simone Salemme"
    },
    {
      "affiliations": [
        "Post Graduate School of Public Health, University of Siena, Siena, Italy"
      ],
      "name": "Domitilla Marconi"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Guido Bellomo"
    },
    {
      "affiliations": [
        "Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Sardegna, Italy"
      ],
      "name": "Sara Maria Pani"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Nicoletta Locuratolo"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Eleonora Lacorte"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Flavia Lucia Lombardo"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Ilaria Bacigalupo"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Elisa Fabrizi"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy",
        "Department of Human Neuroscience, Università degli Studi di Roma La Sapienza, Rome, Lazio, Italy"
      ],
      "name": "Marco Canevelli"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Francesco Sciancalepore"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Patrizia Lorenzini"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Ilaria Palazzesi"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Alice Paggetti"
    },
    {
      "affiliations": [
        "Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Faculty of Medicine and Psychology, Università degli Studi di Roma La Sapienza, Rome, Lazio, Italy"
      ],
      "name": "Francesco Della Gatta"
    },
    {
      "affiliations": [
        "Department of Neuroscience, Istituto Superiore di Sanita, Roma, Italy"
      ],
      "name": "Paola Piscopo"
    },
    {
      "affiliations": [
        "National Centre for Drug Research and Evaluation, Istituto Superiore di Sanita, Roma, Italy"
      ],
      "name": "Emanuela Salvi"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Francesca Zambri"
    },
    {
      "affiliations": [
        "Department of Biomedicine and Prevention, University of Rome Tor Vergata, Roma, Lazio, Italy"
      ],
      "name": "Annachiara Di Nolfi"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Vittorio Palermo"
    },
    {
      "affiliations": [
        "Economic Evaluation and HTA (EEHTA-CEIS), DEF Department, Faculty of Economics, University of Rome Tor Vergata, Roma, Lazio, Italy"
      ],
      "name": "Paolo Sciattella"
    },
    {
      "affiliations": [
        "Economic Evaluation and HTA (EEHTA-CEIS), DEF Department, Faculty of Economics, University of Rome Tor Vergata, Roma, Lazio, Italy"
      ],
      "name": "Chiara Bini"
    },
    {
      "affiliations": [
        "Economic Evaluation and HTA (EEHTA-CEIS), DEF Department, Faculty of Economics, University of Rome Tor Vergata, Roma, Lazio, Italy"
      ],
      "name": "Francesco Saverio Mennini"
    },
    {
      "affiliations": [
        "General directorate for prevention, Ministero della Salute, Roma, Lazio, Italy"
      ],
      "name": "Caterina Bianca Neve Aurora Bianchi"
    },
    {
      "affiliations": [
        "General directorate for prevention, Ministero della Salute, Roma, Lazio, Italy"
      ],
      "name": "Fiammetta Landoni"
    },
    {
      "affiliations": [
        "General directorate for prevention, Ministero della Salute, Roma, Lazio, Italy"
      ],
      "name": "Maria Assunta Giannini"
    },
    {
      "affiliations": [
        "Scientific consultant, Istituto Superiore di Sanita, Roma, Italy"
      ],
      "name": "Teresa Di Fiandra"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy"
      ],
      "name": "Nicola Vanacore"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy",
        "Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy",
        "Post Graduate School of Public Health, University of Siena, Siena, Italy",
        "Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Sardegna, Italy",
        "Department of Human Neuroscience, Università degli Studi di Roma La Sapienza, Rome, Lazio, Italy",
        "Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Faculty of Medicine and Psychology, Università degli Studi di Roma La Sapienza, Rome, Lazio, Italy",
        "Department of Neuroscience, Istituto Superiore di Sanita, Roma, Italy",
        "National Centre for Drug Research and Evaluation, Istituto Superiore di Sanita, Roma, Italy",
        "Department of Biomedicine and Prevention, University of Rome Tor Vergata, Roma, Lazio, Italy",
        "Economic Evaluation and HTA (EEHTA-CEIS), DEF Department, Faculty of Economics, University of Rome Tor Vergata, Roma, Lazio, Italy",
        "General directorate for prevention, Ministero della Salute, Roma, Lazio, Italy",
        "Scientific consultant, Istituto Superiore di Sanita, Roma, Italy"
      ],
      "name": "The National Committee on Dementia of the National Dementia Plan"
    },
    {
      "affiliations": [
        "National Centre for Disease Prevention and Health Promotion, Istituto Superiore di Sanita, Rome, Italy",
        "Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy",
        "Post Graduate School of Public Health, University of Siena, Siena, Italy",
        "Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Sardegna, Italy",
        "Department of Human Neuroscience, Università degli Studi di Roma La Sapienza, Rome, Lazio, Italy",
        "Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Faculty of Medicine and Psychology, Università degli Studi di Roma La Sapienza, Rome, Lazio, Italy",
        "Department of Neuroscience, Istituto Superiore di Sanita, Roma, Italy",
        "National Centre for Drug Research and Evaluation, Istituto Superiore di Sanita, Roma, Italy",
        "Department of Biomedicine and Prevention, University of Rome Tor Vergata, Roma, Lazio, Italy",
        "Economic Evaluation and HTA (EEHTA-CEIS), DEF Department, Faculty of Economics, University of Rome Tor Vergata, Roma, Lazio, Italy",
        "General directorate for prevention, Ministero della Salute, Roma, Lazio, Italy",
        "Scientific consultant, Istituto Superiore di Sanita, Roma, Italy"
      ],
      "name": "The FONDEM Study Group"
    },
    {
      "affiliations": [],
      "name": "National Guideline Working Group"
    }
  ],
  "title": "Advancing dementia care: a review of Italy’s public health response within the WHO Global Action Plan and European strategies",
  "uid": "3ad5b047-9157-504d-bb14-548ab413ad09"
}