{
  "abstract": "Paediatric Blepharokeratoconjunctivitis (pBKC) is a condition characterised by lid margin inflammation and secondary ocular surface disease. Various topical and systemic antibiotics, topical and systemic anti-inflammatory medications, lid cleaning techniques and dietary supplementation are used in its treatment.This is a retrospective review of patients with pBKC presenting to Moorfields Eye Hospital from 2008 to 2024. We collected data on patient demographics, clinical presentation and treatments used.We reviewed the records of 493 patients. Of those meeting eligibility criteria, 50% were male. 65% declared their Ethnicity and 20% were Asian, 16% White, 6% Mixed, 1% Black and 21% Other ethnic group. Mean LogMAR vision at presentation was 0.2 (min -0.1, max 1.8) and at last follow-up was 0.1 (min -0.1, max 1.6). 70% had corneal involvement at presentation, improving to 55% at last follow-up. The most common treatment was topical steroid (92%). Topical antibiotics were used in 80% of cases. 73% of children had systemic antibiotics and 63% received lubricants. Cyclosporine was used in 50% of cases but Tacrolimus only rarely (3%). Lid hygiene was prescribed in 82%. Omega 3 was recommended in 15% of cases.Epithelial involvement was more responsive to treatment than corneal vascularization.The incidence of cPBK presenting to our institution has increased over time, as it has in other parts of the world. There use of Ciclosporin has also increased with time and it is prescribed by general paediatric ophthalmologists as well as in specialist corneal clinics",
  "authors": [
    {
      "affiliations": [
        "Moorfields Eye Hospital, London, UK"
      ],
      "name": "Laila Ibrahim"
    },
    {
      "affiliations": [
        "Moorfields Eye Hospital, London, UK"
      ],
      "name": "Nausheen Hayat"
    },
    {
      "affiliations": [
        "Moorfields Eye Hospital, London, UK"
      ],
      "name": "Annegret Dahlmann-Noor"
    },
    {
      "affiliations": [
        "Moorfields Eye Hospital, London, UK"
      ],
      "name": "Anne-Marie Hinds"
    }
  ],
  "title": "130144 Management and outcomes of paediatric blepharokeratoconjunctivitis in a tertiary care centre",
  "uid": "198caa79-4bc2-5eba-b8b9-cf3e79e066ab"
}