{
  "abstract": "Background Breastfeeding may be associated with lower future risk of maternal type 2 diabetes (T2D). However, existing evidence is inconsistent and derived largely from studies in high-income countries. We assess the association of breastfeeding and breastfeeding duration with incident T2D among Chinese women.Research design and methods The prospective China Kadoorie Biobank recruited 512 724 adults from 10 localities across China between 2004 and 2008. During 11.8 years’ follow-up, 12 011 cases of incident T2D were recorded among 283 855 female participants without prior diabetes. Cox regression was used to estimate adjusted HRs for incident T2D associated with ever breastfeeding, mean breastfeeding duration per child and lifetime breastfeeding duration.Results Overall, 98.6% of female participants were parous, among whom 97.2% reported ever breastfeeding, with mean lifetime breastfeeding duration and breastfeeding duration per child of 34.8 and 14.9 months, respectively. Among parous female participants, there was no clear association between ever breastfeeding and risk of incident T2D (adjusted HR 1.06 (95% CI 0.94 to 1.20)). A modest log-linear positive association was observed between lifetime breastfeeding duration and incident T2D among parous female participants who ever breastfed (1.01 (1.01 to 1.02) per 6 months longer breastfeeding), but this was attenuated after adjustment for parity (1.00 (0.99 to 1.01)). Mean breastfeeding duration per child was not associated with incident T2D (1.01 (0.99 to 1.02) per 6 months longer breastfeeding).Conclusions In this population with almost universal childbearing and breastfeeding, there was no apparent association of ever breastfeeding or of breastfeeding duration with incident T2D.",
  "authors": [
    {
      "affiliations": [
        "Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Johanna Kaminer"
    },
    {
      "affiliations": [
        "Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Christiana Kartsonaki"
    },
    {
      "affiliations": [
        "Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Paul Sherliker"
    },
    {
      "affiliations": [
        "Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Ling Yang"
    },
    {
      "affiliations": [
        "Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Andri Iona"
    },
    {
      "affiliations": [
        "Department of Epidemiology & Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China"
      ],
      "name": "Pei Pei"
    },
    {
      "affiliations": [
        "Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Yiping Chen"
    },
    {
      "affiliations": [
        "Department of Epidemiology & Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China",
        "Peking University Center for Public Health and Epidemic Preparedness & Response, Peking University, Beijing, China",
        "Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China"
      ],
      "name": "Dianjianyi Sun"
    },
    {
      "affiliations": [
        "Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Xiaoming Yang"
    },
    {
      "affiliations": [
        "Suzhou Center for Disease Prevention and Control, Suzhou, Jiangsu, 215004, China, Suzhou, China"
      ],
      "name": "Yan Lu"
    },
    {
      "affiliations": [
        "Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Huaidong Du"
    },
    {
      "affiliations": [
        "Department of Epidemiology & Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China",
        "Peking University Center for Public Health and Epidemic Preparedness & Response, Peking University, Beijing, China",
        "Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China"
      ],
      "name": "Jun Lv"
    },
    {
      "affiliations": [
        "Department of Epidemiology & Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China",
        "Peking University Center for Public Health and Epidemic Preparedness & Response, Peking University, Beijing, China",
        "Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China"
      ],
      "name": "Canqing Yu"
    },
    {
      "affiliations": [
        "China National Center for Food Safety Risk Assessment, Beijing, China"
      ],
      "name": "Junshi Chen"
    },
    {
      "affiliations": [
        "Department of Epidemiology & Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China",
        "Peking University Center for Public Health and Epidemic Preparedness & Response, Peking University, Beijing, China",
        "Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing, China"
      ],
      "name": "Liming Li"
    },
    {
      "affiliations": [
        "Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK"
      ],
      "name": "Zhengming Chen"
    },
    {
      "affiliations": [
        "Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK",
        "Health Data Research UK Oxford, University of Oxford, Oxford, UK"
      ],
      "name": "Fiona Bragg"
    },
    {
      "affiliations": [],
      "name": "China Kadoorie Biobank Collaborative Group"
    }
  ],
  "title": "Breastfeeding and risk of maternal type 2 diabetes: a prospective cohort study of 280 000 women in China",
  "uid": "749bb45e-dccb-507d-b81b-244ac8593335"
}