{
  "abstract": "Introduction A core screening, assessment and outcome set is needed in cancer prehabilitation to standardise what is measured in both research and services. Currently, there is significant variation in measures used, which limits comparability between studies and evidence synthesis. Standardising measures will improve the quality, comparability and impact of research by reducing heterogeneity between studies, minimising reporting bias, improving trial efficiency, enabling data synthesis into large datasets, supporting international collaboration and data sharing, and accelerating the implementation of best practices.Methods and analysis An international Delphi consensus process will be conducted involving patients, healthcare professionals and researchers to identify screening, assessment and outcomes and their corresponding measurement instruments, to be included in a core set. The study consists of three phases: (1) A scoping review to identify screening, assessment and outcomes and associated measurement instruments currently used in cancer prehabilitation. (2) At least two rounds of a modified Delphi survey to prioritise the identified screening, assessment and outcomes using a 1–9 Likert scale. Consensus will be defined across stakeholder groups using prespecified thresholds. A consensus meeting will be held if agreement is not reached. (3) Measurement instruments corresponding to each retained screening, assessment and outcome will be assessed for quality for measurement properties and feasibility. Further Delphi rounds will be conducted to reach consensus on the most appropriate measurement instrument for each core screening, assessment and outcome.Ethics and dissemination The study has ethical approval (Ref: 25/NW/0159). Findings will be disseminated through peer-reviewed publications, conference presentations, stakeholder networks and made publicly available via the Core Outcome Measures in Effectiveness Trials database.",
  "authors": [
    {
      "affiliations": [
        "Academy of Sport and Physical Activity, Physical activity, Wellness and Public Health Research Group, Sheffield Hallam University, Sheffield, UK",
        "Advanced Wellbeing Research Centre, Sheffield Hallam University, Sheffield, UK"
      ],
      "name": "Thomas Parkington"
    },
    {
      "affiliations": [
        "Academy of Sport and Physical Activity, Physical activity, Wellness and Public Health Research Group, Sheffield Hallam University, Sheffield, UK",
        "Advanced Wellbeing Research Centre, Sheffield Hallam University, Sheffield, UK"
      ],
      "name": "Liam John Humphreys"
    },
    {
      "affiliations": [
        "Academic Surgery, Cancer Sciences, University of Southampton Faculty of Medicine, Southampton, UK",
        "NIHR Southampton Biomedical Research Centre, Perioperative Medicine and Critical Care Theme, University Hospital Southampton, Southampton, UK"
      ],
      "name": "Malcolm West"
    },
    {
      "affiliations": [
        "Academy of Sport and Physical Activity, Physical activity, Wellness and Public Health Research Group, Sheffield Hallam University, Sheffield, UK",
        "Advanced Wellbeing Research Centre, Sheffield Hallam University, Sheffield, UK"
      ],
      "name": "Anna Myers"
    },
    {
      "affiliations": [
        "Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, England, UK"
      ],
      "name": "Carol Keen"
    },
    {
      "affiliations": [
        "Department of Physiotherapy, The University of Melbourne, Melbourne, Victoria, Australia",
        "Centre for Health Services Research in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia",
        "The Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia"
      ],
      "name": "Linda Denehy"
    },
    {
      "affiliations": [
        "School of Human Nutrition, McGill University, Montreal, Quebec, Canada",
        "Department of Surgery, McGill University, Montreal, Quebec, Canada",
        "Department of Anesthesia, McGill University, Montreal, Quebec, Canada"
      ],
      "name": "Chelsia Gillis"
    },
    {
      "affiliations": [
        "Department of Physiotherapy, The University of Melbourne, Melbourne, Victoria, Australia",
        "Centre for Health Services Research in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia"
      ],
      "name": "Lara Edbrooke"
    },
    {
      "affiliations": [
        "GM Cancer Clinical Director for Prehabilitation and Recovery University of Manchester and Manchester Metropolitan University, Manchester, UK"
      ],
      "name": "John Moore"
    },
    {
      "affiliations": [
        "Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, New South Wales, Australia",
        "Faculty of Medicine and Health, Central Clinical School, University of Sydney CAR, Sydney, New South Wales, Australia",
        "Institute of Academic Surgery (IAS), Royal Prince Alfred Hospital, Sydney, New South Wales, Australia"
      ],
      "name": "Daniel Steffens"
    },
    {
      "affiliations": [
        "Department of Surgery, Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands",
        "Department of Nutrition and Movement Sciences, Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands"
      ],
      "name": "Bart C Bongers"
    },
    {
      "affiliations": [
        "Surgical Oncology, Maxima Medical Centre Location Veldhoven, Veldhoven, Noord-Brabant, The Netherlands"
      ],
      "name": "Gerrit D Slooter"
    },
    {
      "affiliations": [
        "Patient Author, Yorkshire Cancer Research, Harrogate, UK"
      ],
      "name": "Karen Nile"
    },
    {
      "affiliations": [
        "Patient Author, Yorkshire Cancer Research, Harrogate, UK"
      ],
      "name": "Neil Garner"
    },
    {
      "affiliations": [
        "Advanced Wellbeing Research Centre, Sheffield Hallam University, Sheffield, UK"
      ],
      "name": "Robert Copeland"
    },
    {
      "affiliations": [],
      "name": "The National Cancer Prehabilitation Coll The Royal Marsden Cancer Charity"
    }
  ],
  "title": "Development of a core screening, assessment and outcome set for cancer prehabilitation: an international Delphi consensus study protocol",
  "uid": "881d1675-3f28-5f3c-9be4-53538c8be0ba"
}