{
  "abstract": "Objectives Post-COVID-19 respiratory infection patterns require updated epidemiological data. To investigate the prevalence and infection patterns of upper respiratory tract infections (URTIs), a survey was conducted to assess the presence of influenza A (IFV A), influenza B (IFV B), respiratory syncytial virus (RSV), human rhinovirus (HRV), adenovirus (Adv), and SARS-CoV-2 among outpatients diagnosed with URTIs.Design A community-based cross-sectional study.Setting Three cities in Sichuan, China.Participants 1174 outpatients diagnosed with URTIs from December 2023 to February 2024.Methods Oropharyngeal swabs were collected using sterile flocked swabs, preserved at 4°C and analysed within 24 hours. Viral nucleic acid was extracted automatically and detected via multiplex PCR-melting curve analysis.Results Results showed in positive detection rates varied significantly by age (p<0.001), peaking in children (77.42%), followed by adolescents (73.23%), adults (63.59%) and older adults (57.58%). IFV B and A predominated, followed by HRV, Adv, RSV and SARS-CoV-2. 12 co-infection types were identified, with HRV/Adv and IFV B/HRV most prevalent. In children and adolescents, co-infections were significantly more common, with predominant types including HRV/Adv, HRV/RSV and RSV/IFV B.Conclusions This study reveals persistent influenza dominance and age-stratified co-infection risks and provides critical baseline data for optimising respiratory infectious disease control in the post-pandemic era.",
  "authors": [
    {
      "affiliations": [
        "Department of Pulmonary and Critical Care Medicine, Wenjiang District People’s Hospital of Chengdu, Chengdu, China"
      ],
      "name": "Ying Li"
    },
    {
      "affiliations": [
        "Department of Obstetrics and Gynecology, Mianyang People’s Hospital, Mianyang, China"
      ],
      "name": "Wei Yin"
    },
    {
      "affiliations": [
        "Department of Pediatrics, Bazhong Maternal and Child Health Hospital, Bazhong, China"
      ],
      "name": "Li Zhang"
    },
    {
      "affiliations": [
        "Department of Pediatrics, Pingchang County Maternity and Child Healthcare Hospital, Bazhong, China"
      ],
      "name": "Ming Sun"
    },
    {
      "affiliations": [
        "Department of Reagent Research and Development, Capitalbio Technology (Chengdu), Chengdu, China"
      ],
      "name": "Qun Yang"
    },
    {
      "affiliations": [
        "Department of Pediatrics, Mianyang People’s Hospital, Mianyang, China"
      ],
      "name": "Sheng Ren"
    },
    {
      "affiliations": [
        "Research and Development Department, Fujian CapitalBio Medical Laboratory, Fuzhou, China"
      ],
      "name": "Xiaoying Lin"
    },
    {
      "affiliations": [
        "Department of Pediatrics, Bazhong Maternal and Child Health Hospital, Bazhong, China"
      ],
      "name": "Jinsong Liu"
    },
    {
      "affiliations": [
        "Department of Reagent Research and Development, Capitalbio Technology (Chengdu), Chengdu, China"
      ],
      "name": "Jiawen Yang"
    },
    {
      "affiliations": [
        "Department of Pediatrics, Sichuan Provincial Maternity and Child Health Care Hospital, Chengdu, China"
      ],
      "name": "Shuyao Zhu"
    },
    {
      "affiliations": [
        "Department of Pulmonary and Critical Care Medicine, Wenjiang District People’s Hospital of Chengdu, Chengdu, China"
      ],
      "name": "Wei Li"
    },
    {
      "affiliations": [
        "Department of Laboratory Medicine, Sichuan Provincial Maternity and Child Health Care Hospital, Chengdu, China"
      ],
      "name": "Hongquan Luo"
    },
    {
      "affiliations": [
        "Department of Reagent Research and Development, Capitalbio Technology (Chengdu), Chengdu, China"
      ],
      "name": "Xin Chen"
    },
    {
      "affiliations": [
        "Research and Development Department, Fujian CapitalBio Medical Laboratory, Fuzhou, China",
        "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China"
      ],
      "name": "Yiyuan Xu"
    },
    {
      "affiliations": [
        "School of Intelligent Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China",
        "Department of Laboratory Medicine, Fujian Medical University, Fuzhou, China"
      ],
      "name": "Guanbin Zhang"
    }
  ],
  "title": "Cross-sectional study of respiratory virus infections in upper respiratory tract infection patients: post-COVID-19 pandemic trends in Sichuan, China",
  "uid": "a56cac81-fdd9-5fd5-8ad6-55d7f74c63bd"
}