{
  "abstract": "Introduction More than 300 million major surgical procedures are carried out under general anaesthesia each year worldwide, and advanced airway management remains one of the leading daily challenges for clinicians. Data from large international prospective cohort studies on adverse events such as cardiovascular collapse, cardiac arrest and severe hypoxaemia during advanced airway management to facilitate anaesthesia are lacking.Methods and analysis The International ob Servational sTudy on AiRway manaGement in operAting room and non-operaTing room anaEsthesia (STARGATE) study will be an international prospective observational cohort study describing the incidence of major adverse events associated with advanced airway management (tracheal intubation or supraglottic airway device placement) for general anaesthesia in the operating and non-operating room for surgery and medical procedures. The secondary aim will be to describe the practice of airway management in a large international cohort. Critically ill patients will be excluded from this study. Data on patients’ characteristics, type of procedure and the adopted airway management strategy, post-procedure adverse events, operator characteristics and in-hospital mortality will be prospectively collected. The study aims to enrol 10 500 patients.Ethics and dissemination The study has been approved by the Ethics Committee of the coordinating centre (Comitato Etico Interaziendale AOU San Luigi Gonzaga, N° 25/2023). Each of the participating centres will then seek approval of their local Ethics Committee before enrolment. Data will be disseminated to the scientific community by original articles submitted to international peer-reviewed journals.Trial registration number NCT05759299.",
  "authors": [
    {
      "affiliations": [
        "Department of Oncology, University of Turin, Turin, Italy",
        "Department of Anesthesiology and Intensive Care, San Luigi Gonzaga University Hospital, Orbassano, Piedmont, Italy"
      ],
      "name": "Vincenzo Russotto"
    },
    {
      "affiliations": [
        "Azienda Sanitaria Locale TO4, Turin, Italy"
      ],
      "name": "Chiara Sansovini"
    },
    {
      "affiliations": [
        "Department of Anaesthesia and Intensive Care, Mater Misericordiae University Hospital, Dublin, Ireland",
        "Department of Surgical Sciences, University of Turin, Turin, Italy"
      ],
      "name": "Massimo Muraccini"
    },
    {
      "affiliations": [
        "Department of Surgical Sciences, University of Turin, Turin, Italy",
        "AOU Città della Salute e della Scienza, Turin, Italy"
      ],
      "name": "Francesca Collino"
    },
    {
      "affiliations": [
        "Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India"
      ],
      "name": "Sheila Nainan Myatra"
    },
    {
      "affiliations": [
        "Anaesthesia and Intensive Care Medicine, Warrington Teaching Hospitals NHS Foundation Trust, Warrington, UK"
      ],
      "name": "Andrew Higgs"
    },
    {
      "affiliations": [
        "Intensive Care Unit, Cabrini Hospital, Malvern, Victoria, Australia",
        "Central Clinical School, Monash University, Melbourne, Victoria, Australia"
      ],
      "name": "David Brewster"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Reanimatology, Intensive medicine and Pain Therapy, University Hospital Centre Zagreb, Zagreb. School of Medicine, University of Zagreb, Zagreb, Croatia"
      ],
      "name": "Renata Curić Radivojević"
    },
    {
      "affiliations": [
        "Department of Anesthesiology and Pain Medicine, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada",
        "Department of Anesthesia and Pain Management, Toronto General Hospital, Toronto, Ontario, Canada"
      ],
      "name": "Matteo Parotto"
    },
    {
      "affiliations": [
        "Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas, USA"
      ],
      "name": "Kunal Karamchandani"
    },
    {
      "affiliations": [
        "Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy",
        "School of Medicine, Vita-Salute San Raffaele University, Milan, Italy"
      ],
      "name": "Giovanni Landoni"
    },
    {
      "affiliations": [
        "Hospital Giovanni Paolo II, Ragusa, Italy",
        "University of Enna, Enna, Italy"
      ],
      "name": "Massimiliano Sorbello"
    },
    {
      "affiliations": [
        "Department of Surgical Sciences, University of Turin, Turin, Italy"
      ],
      "name": "Mattia Monfroglio"
    },
    {
      "affiliations": [
        "Department of Surgical Sciences, University of Turin, Turin, Italy"
      ],
      "name": "Giulia Rovescala"
    },
    {
      "affiliations": [
        "Department of Surgical Sciences, University of Turin, Turin, Italy"
      ],
      "name": "Pietro Martinelli"
    },
    {
      "affiliations": [
        "Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy"
      ],
      "name": "Ornella Tinelli"
    },
    {
      "affiliations": [
        "Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy"
      ],
      "name": "Jennifer Meessen"
    },
    {
      "affiliations": [
        "School of Medicine and Surgery, University of Trento, Trento, Italy",
        "Anesthesia and Intensive Care, Santa Chiara Hospital, Trento, Italy"
      ],
      "name": "Giacomo Bellani"
    },
    {
      "affiliations": [
        "Anesthesia and Intensive Care Medicine, School of Medicine, University of Galway, Galway, Ireland",
        "Department of Anaesthesia and Intensive Care Medicine, University Hospital Galway, Galway, Ireland"
      ],
      "name": "John G Laffey"
    },
    {
      "affiliations": [
        "Department of Anesthesia and Intensive Care, University Hospital of Brest, Brest, France",
        "Laboratory ORPHY, University of Brest, Brest, France"
      ],
      "name": "Olivier Langeron"
    },
    {
      "affiliations": [
        "Department of Oncology, University of Turin, Turin, Italy",
        "Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy"
      ],
      "name": "Pietro Caironi"
    }
  ],
  "title": "Multicentre international observational study on airway management for anaesthesia: the STARGATE study protocol",
  "uid": "1894c94f-04b9-544b-b047-d44a99365af4"
}