{
  "abstract": "Introduction Older adults with cancer have ageing-related vulnerabilities that influence their treatment tolerance and decision-making. In our previous randomised controlled trial (MAPLE), integrating geriatric assessment (GA) with communication support using a question prompt list (QPL), delivered by trained intervention providers, facilitated patient–oncologist communication, increased implementation of GA-guided management (GAM) and improved patient outcomes. However, its widespread adoption has been limited by the need for trained personnel and dedicated time. To enhance scalability and sustainability, we developed a mobile application-based intervention to deliver GAM and communication support. This MAPLE2 study aims to evaluate the feasibility of the intervention using this mobile application-based GA and QPL among older adults with cancer.Methods and analysis This multicentre, open-label, pilot randomised controlled trial will be conducted at two academic hospitals in Japan. Patients aged≥70 years with solid cancer or lymphoma initiating or changing systemic therapy will undergo baseline GA. Patients with any GA impairment will be randomised to receive either (1) a mobile application-based intervention providing feedback of GA summary with tailored GAM recommendations and QPL or (2) usual care. The primary endpoint is the proportion of participants who complete all of the following interventions using the mobile application: (1) self-administered GA, (2) receipt of the tailored GAM recommendations and QPL and (3) confirmation that their oncologists review the tailored GAM recommendations and QPL at subsequent visits. Forty participants are planned to be enrolled.Ethics and dissemination The study has been approved by the Institutional Review Board of the National Cancer Center, Japan (approval number: 2025-089). Written informed consent will be obtained from all participants. Results will be presented at academic conferences and published in peer-reviewed journals.Trial status Recruitment has been initiated from 8 September 2025 and is planned to be completed by 31 August 2026, with a follow-up period by 31 August 2027.Trial registration number UMIN000058887",
  "authors": [
    {
      "affiliations": [
        "Division of Survivorship Research, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan"
      ],
      "name": "Ayumu Matsuoka"
    },
    {
      "affiliations": [
        "Division of Survivorship Research, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan"
      ],
      "name": "Yukiko Konishi"
    },
    {
      "affiliations": [
        "Department of Oncology and General Medicine, IMSUT Hospital, Institute of Medical Science, University of Tokyo, Tokyo, Japan"
      ],
      "name": "Narikazu Boku"
    },
    {
      "affiliations": [
        "Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan"
      ],
      "name": "Atsuo Takashima"
    },
    {
      "affiliations": [
        "Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan"
      ],
      "name": "Takuji Okusaka"
    },
    {
      "affiliations": [
        "Department of Biostatistics, Shizuoka Cancer Center, Shizuoka, Japan"
      ],
      "name": "Keita Mori"
    },
    {
      "affiliations": [
        "Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"
      ],
      "name": "Tatsuo Akechi"
    },
    {
      "affiliations": [
        "Department of Respirology, Graduate School of Medicine, Gifu University, Gifu, Japan"
      ],
      "name": "Yukari Tsubata"
    },
    {
      "affiliations": [
        "NPO Pancreatic Cancer Action Network Japan, Tokyo, Japan"
      ],
      "name": "Yoshiyuki Majima"
    },
    {
      "affiliations": [
        "Department of Cancer Survivorship and Digital Medicine, Jikei University School of Medicine, Tokyo, Japan"
      ],
      "name": "Yosuke Uchitomi"
    },
    {
      "affiliations": [
        "Department of Medical Oncology, Kyorin University Faculty of Medicine, Tokyo, Japan"
      ],
      "name": "Fumio Nagashima"
    },
    {
      "affiliations": [
        "Division of Survivorship Research, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan"
      ],
      "name": "Maiko Fujimori"
    }
  ],
  "title": "Feasibility of a mobile application-based geriatric assessment and communication support intervention for older adults with cancer: protocol for a pilot randomised controlled trial (MAPLE2 pilot)",
  "uid": "e7eb48d1-6fab-59b8-85a9-fd9bf86412ea"
}