{
  "abstract": "Introduction Herpes zoster (HZ) vaccinations effectively prevent HZ and may decrease dementia, but HZ vaccine uptake remains poor in China. Rapid verbal persuasion is an innovative intervention, in which physicians offered brief advice to encourage individuals to accept vaccination. This study aims to tailor this intervention to promote HZ vaccination among older adults.Methods and analysis The proposed study will be a two-arm randomised controlled trial and conducted across four community health centres in Shenzhen, China. A total of 388 participants aged 50 and above will be recruited and assigned to either the intervention arm or the standard-care arm. The primary outcome will be first-dose uptake, recorded within 3 weeks after intervention. The primary outcome will be calculated for each arm and compared using χ 2 test.Ethics and dissemination This trial has been approved by the Ethics Committee of Southern Medical University (Ethical Approval (2024) No. 90). Our findings will be disseminated to patients, healthcare providers and stakeholders through outreach activities and published in peer-reviewed journals, as well as presented in scientific conferences to inform future research or evidence-based practices for public health promotion.Trial registration number Chinese Clinical Trial Registry (No. ChiCTR2500100798). Registered on 15 April 2025.",
  "authors": [
    {
      "affiliations": [
        "Acacia Lab for Implementation Science, School of Health Management, Southern Medical University, Guangzhou, Guangdong, China"
      ],
      "name": "Zizhen Huang"
    },
    {
      "affiliations": [
        "Southern Medical University Institute for Global Health, Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China"
      ],
      "name": "Qing-Qing Li"
    },
    {
      "affiliations": [
        "Department of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China"
      ],
      "name": "Zhixiang Tang"
    },
    {
      "affiliations": [
        "Acacia Lab for Implementation Science, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China"
      ],
      "name": "Siyuan Liu"
    },
    {
      "affiliations": [
        "Southern Medical University Institute for Global Health, Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China"
      ],
      "name": "Dongmei Zhong"
    },
    {
      "affiliations": [
        "Department of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China"
      ],
      "name": "Qunzhi Sun"
    },
    {
      "affiliations": [
        "Department of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China"
      ],
      "name": "Junyao Wang"
    },
    {
      "affiliations": [
        "Department of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China"
      ],
      "name": "Xiaoshan Huang"
    },
    {
      "affiliations": [
        "Department of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China"
      ],
      "name": "Yuting Qiu"
    },
    {
      "affiliations": [
        "Acacia Lab for Implementation Science, School of Health Management, Southern Medical University, Guangzhou, Guangdong, China"
      ],
      "name": "Junlin Zhu"
    },
    {
      "affiliations": [
        "Acacia Lab for Implementation Science, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China"
      ],
      "name": "Xiaoqing Zhu"
    },
    {
      "affiliations": [
        "Southern Medical University Institute for Global Health, Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China"
      ],
      "name": "Run Wang"
    },
    {
      "affiliations": [
        "Southern Medical University Institute for Global Health, Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China"
      ],
      "name": "Wenjun He"
    },
    {
      "affiliations": [
        "Shenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, China"
      ],
      "name": "Rui Zhao"
    },
    {
      "affiliations": [
        "Shenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, China"
      ],
      "name": "Mengjun Zhang"
    },
    {
      "affiliations": [
        "Shenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, China"
      ],
      "name": "Huanyuan Luo"
    },
    {
      "affiliations": [
        "Department of General Practice, The Second Affiliated Hospital of the Chinese University of Hong Kong - Shenzhen, Shenzhen, Guangdong, China"
      ],
      "name": "Changxia Luo"
    },
    {
      "affiliations": [
        "Southern Medical University Institute for Global Health, Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, China",
        "Center for World Health Organization Studies, School of Health Management, Southern Medical University, Guangzhou, Guangdong, China"
      ],
      "name": "Dong Roman Xu"
    }
  ],
  "title": "Effectiveness of rapid verbal persuasion in promoting herpes zoster vaccination among older adults in China: study protocol of a two-arm randomised controlled trial",
  "uid": "8269bbfa-c984-51d1-93e2-94baf88b3504"
}