{
  "abstract": "Introduction Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple body parts. With a fluctuating range of symptoms, SLE imposes significant challenges and limitations on individuals at work. The objective of this review is to synthesise the existing literature on work disability in patients with SLE and identify factors associated with work disability and facilitators of returning to work (RTW).Methods and analysis This systematic review is registered with PROSPERO (CRD420251011567). This protocol followed the PRISMA-P (Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Protocols) guidelines. The search will be conducted using Business Source Premier, CINAHL, Cochrane Library, Embase, MEDLINE, PsycINFO, Scopus and Web of Science from inception to March 2025. At least two independent reviewers will complete screening, data extraction and critical appraisal. Eligible studies will focus on individuals with SLE and examine the barriers and facilitators to RTW. Eligible studies will be peer-reviewed, published in English or available in English translations. Unpublished research, opinion pieces, conference papers, abstracts, book chapters, knowledge syntheses, commentaries and grey literature will be excluded.Ethics and dissemination This study does not require ethics approval. The results of the completed review will be published.PROSPERO registration number CRD420251011567.",
  "authors": [
    {
      "affiliations": [
        "Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Ontario, Canada",
        "Krembil Research Institute, Toronto, Ontario, Canada",
        "Centre for Research in Occupational Safety & Health, Laurentian University, Sudbury, Ontario, Canada"
      ],
      "name": "Behdin Nowrouzi-Kia"
    },
    {
      "affiliations": [
        "Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Ontario, Canada"
      ],
      "name": "Joyce Lo"
    },
    {
      "affiliations": [
        "Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Ontario, Canada"
      ],
      "name": "Bao-Zhu Stephanie Long"
    },
    {
      "affiliations": [
        "Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Ontario, Canada"
      ],
      "name": "Kishana Balakrishnar"
    },
    {
      "affiliations": [
        "Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Ontario, Canada"
      ],
      "name": "Aishvinigaa Sathananthan"
    },
    {
      "affiliations": [
        "Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Ontario, Canada"
      ],
      "name": "Mandaakini Choppella"
    },
    {
      "affiliations": [
        "University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada",
        "Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada"
      ],
      "name": "Zahi Touma"
    }
  ],
  "title": "Work disability in systemic lupus erythematosus: a systematic review protocol of contributing factors and return-to-work facilitators",
  "uid": "20d19cd9-afb8-5b98-8aa5-4168c1bb12bb"
}