{
  "abstract": "Objective This study aimed to explore the mediating role of inspiratory muscle strength between abdominal obesity and lung function in young people.Design Cross-sectional study.Setting This survey was conducted in Peking University Health Science Center, Beijing, China.Participants 404 subjects aged 18 and older.Main outcome measures Forced expiratory volume in one second percent (FEV1%) predicted ≥80% was defined as the normal lung function.Results A total of 404 subjects were included, with maximal inspiratory pressure of 65.27±29.55 cmH 2O. Among them, 61 subjects (15.10%) had central obesity, 106 subjects (26.24%) had a FEV1% predicted <80%. Abdominal obesity was significantly associated with lung function (OR=5.356, 95% CI 2.391 to 11.999, p<0.001) and inspiratory muscle strength (OR=3.537, 95% CI 1.441 to 8.679, p=0.006). Even after adjusting for inspiratory muscle strength, the relationship between abdominal obesity and lung function remained significant (OR=4.723, 95% CI 2.076 to 10.749, p<0.001), and there was a significant association between inspiratory muscle strength and lung function (OR=0.322, 95% CI 0.176 to 0.591, p<0.001). The z-test confirmed that inspiratory muscle strength mediated the relationship between abdominal obesity and lung function (|z|=2.14, p<0.05).Conclusion This study highlighted the mediating role of inspiratory muscle strength between abdominal obesity and lung function.",
  "authors": [
    {
      "affiliations": [
        "Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China"
      ],
      "name": "Cui Wang"
    },
    {
      "affiliations": [
        "Peking University School of Nursing, Beijing, China"
      ],
      "name": "Zeng Wen"
    },
    {
      "affiliations": [
        "Peking University School of Nursing, Beijing, China"
      ],
      "name": "Yetian Liang"
    },
    {
      "affiliations": [
        "Medical College, Xinyang Normal University, Xinyang, Henan, China"
      ],
      "name": "Minghao Pan"
    },
    {
      "affiliations": [
        "Peking University School of Nursing, Beijing, China"
      ],
      "name": "Shaomei Shang"
    }
  ],
  "title": "Mediating role of inspiratory muscle strength in the relationship between abdominal obesity and lung function in young individuals: a cross-sectional study",
  "uid": "90274aa6-e8a7-5a59-8b30-4a7f3a5c3309"
}