{
  "abstract": "Objective This study analysed the clinical outcomes and healthcare costs associated with diabetic foot ulcer (DFU) within a tertiary healthcare centre in Singapore.Design This is a retrospective, single-centre study. Patient data were extracted from the hospital’s electronic health system, including demographic, clinical and hospitalisation information. Hospitalisation costs were categorised into DFU-related and other hospitalisation costs. A one-way sensitivity analysis was performed to estimate the total healthcare costs associated with DFU.Setting Tertiary centre within a population suffering from a diabetic epidemic.Participants All patients aged 18 years or older who received DFU treatment between January 2019 and December 2023 at the Singapore General Hospital were included.Results A total of 2857 DFU patients were included in the study. In-hospital mortality remained stable at 5%–6% annually. Among the cohort, 39.1% underwent minor amputations, 19.6% had major amputations and 9.0% experienced both minor and major amputations. The median length of stay for surgical patients ranged from 10 (IQR 4–24) to 13 days (IQR 6–31), compared with 4 (IQR 2–8) to 5 (IQR 3–9.5) days for non-surgical patients. Total costs per admission for patients with DFU-related surgery ranged from US$28 588.96 to US$34 204.77, while for those without surgery, costs ranged from US$6637.59 to US$7955.23. Total hospitalisation costs for DFU during the study period ranged from US$65.87 million to US$72.16 million. All figures were inflation adjusted to 2023 US dollars.Conclusions DFU poses a significant clinical and economic burden in Singapore. Understanding the costs associated with DFU is essential for resource allocation and planning in DFU management.",
  "authors": [
    {
      "affiliations": [
        "Department of Vascular Surgery, Singapore General Hospital, Singapore, Singapore"
      ],
      "name": "Adrian Choon Kwang Chia"
    },
    {
      "affiliations": [
        "Group Finance Analytics, Singapore Health Services Pte Ltd, Singapore, Singapore"
      ],
      "name": "Ivan En-Howe Tan"
    },
    {
      "affiliations": [
        "Group Finance Analytics, Singapore Health Services Pte Ltd, Singapore, Singapore"
      ],
      "name": "Zi Ning Tan"
    },
    {
      "affiliations": [
        "Group Finance Analytics, Singapore Health Services Pte Ltd, Singapore, Singapore"
      ],
      "name": "Wen Jing Yeo"
    },
    {
      "affiliations": [
        "Group Finance Analytics, Singapore Health Services Pte Ltd, Singapore, Singapore"
      ],
      "name": "Yun Zhao"
    },
    {
      "affiliations": [
        "Department of Vascular Surgery, Singapore General Hospital, Singapore, Singapore"
      ],
      "name": "Charyl Jia Qi Yap"
    },
    {
      "affiliations": [
        "Finance, Singapore General Hospital, Singapore, Singapore"
      ],
      "name": "Kwok Ann Ang"
    },
    {
      "affiliations": [
        "Group Finance Analytics, Singapore Health Services Pte Ltd, Singapore, Singapore",
        "Finance, Regional Health System & Strategic Finance, Singapore Health Services Pte Ltd, Singapore, Singapore"
      ],
      "name": "Marianne Kit Har Au"
    },
    {
      "affiliations": [
        "Department of Vascular Surgery, Singapore General Hospital, Singapore, Singapore"
      ],
      "name": "Tze Tec Chong"
    }
  ],
  "title": "Retrospective analysis of value-driven outcomes of diabetic foot ulcer in a tertiary hospital in Singapore",
  "uid": "b38ac28a-498f-54fe-987b-c5693d2cf640"
}