{
  "abstract": "Objectives To compare the quality and time efficiency of physician-written summaries with customised large language model (LLM)-generated medical summaries integrated into the electronic health record (EHR) in a non-English clinical environment.Design Cross-sectional non-inferiority validation study.Setting Tertiary academic hospital.Participants 52 physicians from 8 specialties at a large Dutch academic hospital participated, either in writing summaries (n=42) or evaluating them (n=10).Interventions Physician writers wrote summaries of 50 patient records. LLM-generated summaries were created for the same records using an EHR-integrated LLM. An independent, blinded panel of physician evaluators compared physician-written summaries to LLM-generated summaries.Primary and secondary outcome measures Primary outcome measures were completeness, correctness and conciseness (on a 5-point Likert scale). Secondary outcomes were preference and trust, and time to generate either the physician-written or LLM-generated summary.Results The completeness and correctness of LLM-generated summaries did not differ significantly from physician-written summaries. However, LLM summaries were less concise (3.0 vs 3.5, p=0.001). Overall evaluation scores were similar (3.4 vs 3.3, p=0.373), with 57% of evaluators preferring LLM-generated summaries. Trust in both summary types was comparable, and interobserver variability showed excellent reliability (intraclass correlation coefficient 0.975). Physicians took an average of 7 min per summary, while LLMs completed the same task in just 15.7 s.Conclusions LLM-generated summaries are comparable to physician-written summaries in completeness and correctness, although slightly less concise. With a clear time-saving benefit, LLMs could help reduce clinicians’ administrative burden without compromising summary quality.",
  "authors": [
    {
      "affiliations": [
        "Department of Otolaryngology – Head and Neck Surgery, University Medical Centre Groningen, Groningen, The Netherlands",
        "Department of Medical Information Technology, University Medical Centre Groningen, Groningen, The Netherlands"
      ],
      "name": "Rosanne C Schoonbeek"
    },
    {
      "affiliations": [
        "Department of Intensive Care, Elisabeth-TweeSteden Ziekenhuis, Tilburg, The Netherlands",
        "Department of Adult Intensive Care, Erasmus MC University Medical Center, Erasmus Universiteit Rotterdam, Rotterdam, The Netherlands"
      ],
      "name": "Jessica D Workum"
    },
    {
      "affiliations": [
        "Board of Directors, University Medical Center, University Medical Centre Groningen, Groningen, The Netherlands"
      ],
      "name": "Stephanie C E Schuit"
    },
    {
      "affiliations": [
        "Department of Medical Information Technology, University Medical Centre Groningen, Groningen, The Netherlands"
      ],
      "name": "Anne H Hoekman"
    },
    {
      "affiliations": [
        "Department of Medical Information Technology, University Medical Centre Groningen, Groningen, The Netherlands"
      ],
      "name": "Tarannom Mehri"
    },
    {
      "affiliations": [
        "Orthopaedic Surgery, University Medical Centre Groningen, Groningen, The Netherlands"
      ],
      "name": "Job N Doornberg"
    },
    {
      "affiliations": [
        "Universitair Medisch Centrum Groningen, Groningen, The Netherlands"
      ],
      "name": "Tom P van der Laan"
    },
    {
      "affiliations": [
        "Department of Medical Information Technology, University Medical Centre Groningen, Groningen, The Netherlands",
        "Department of Pediatrics, University Medical Centre Groningen, Groningen, The Netherlands"
      ],
      "name": "Charlotte M H H T Bootsma-Robroeks"
    },
    {
      "affiliations": [],
      "name": "On behalf of the Applied Artificial Intelligence in Healthcare Consortium"
    }
  ],
  "title": "Quality and efficiency of integrating customised large language model-generated summaries versus physician-written summaries: a validation study",
  "uid": "666320ac-8194-5e47-94c3-261a17ab524d"
}
