{
  "abstract": "Objectives Hypotension frequently occurs following the initiation of general anaesthesia, particularly in older individuals, and is linked to adverse postoperative consequences when it is severe. This study was designed to compare the predictive effects of carotid ultrasound measurements and inferior vena cava (IVC) ultrasound measurements on postinduction hypotension (PIH) in older patients.Design Prospective observational study.Methods A total of 102 older adults who were scheduled for elective gastrointestinal surgery were included in the study. Before general anaesthesia induction, maximum IVC diameter (dIVCmax), minimum IVC diameter (dIVCmin), collapsibility index of IVC (IVC-CI), respiratory variation in carotid artery blood flow peak velocity (ΔVpeak) and carotid corrected flow time (FTc) were measured by ultrasound. FTc(B) and FTc(W) were calculated by applying Bazett’s formula and Wodey’s formula, respectively. Patients were divided into hypotensive and non-hypotension group according to whether the systolic blood pressure (SBP) decreased more than 30% from the baseline or the absolute value of SBP was less than 90 mm Hg within 15 min after anaesthesia induction.Results After the induction, hypotension was observed in 49% of the patients. The area under the receiver operating characteristics curve (AUROC) of FTc(W), FTc(B) and △Vpeak for predicting PIH were 0.815, 0.691 and 0.713; the optimal cut-off values were 334.7 ms, 348.3 ms and 6.35%, respectively. The AUROC of IVC-CI, dIVCmax and dIVCmin for predicting PIH were 0.666, 0.680 and 0.702; the optimal cut-off values were 46%, 0.985 cm and 0.635 cm, respectively. The AUC of the FTc(W) was significantly higher than that of the FTc(B) (p=0.003), IVC-CI (p=0.024) and dIVCmax (p=0.046).Conclusions The FTc(W) values measured by ultrasonography were more accurate for predicting PIH in the older patients as compared with dIVCmax and IVC-CI. Furthermore, the predictive accuracy of FTc(W) is better than FTc(B).Trial registration number ChiCTR2100054532.",
  "authors": [
    {
      "affiliations": [
        "Center for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China",
        "Research Institute of Anesthesiology and Perioperative Medicine, Hangzhou Medical College, Hangzhou, Zhejiang, China"
      ],
      "name": "Jiafeng Fu"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Nanchang Hongdu Hospital of TCM, Nanchang, Jiangxi, China"
      ],
      "name": "Qing Li"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China"
      ],
      "name": "Xiaoping Zhu"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China"
      ],
      "name": "Weihong Zhao"
    },
    {
      "affiliations": [
        "Center for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China",
        "Research Institute of Anesthesiology and Perioperative Medicine, Hangzhou Medical College, Hangzhou, Zhejiang, China"
      ],
      "name": "Yanfei Lu"
    },
    {
      "affiliations": [
        "Center for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China",
        "Research Institute of Anesthesiology and Perioperative Medicine, Hangzhou Medical College, Hangzhou, Zhejiang, China"
      ],
      "name": "Foquan Luo"
    }
  ],
  "title": "Comparing predictive accuracy of carotid artery ultrasonography with inferior vena cava ultrasonography for predicting postinduction hypotension in older patients: a prospective observational study",
  "uid": "76ba63e2-4ab9-5e52-b8ed-ec3d014ade5e"
}