{
  "abstract": "Objectives To investigate whether positive cognitive emotion regulation (PCER) and sense of coherence (SOC) mediate the relationship between family hardiness (FH) and post-traumatic growth (PTG) in patients with lung cancer undergoing chemotherapy.Design Cross-sectional study, convenience sampling method and mediation analyses.Setting All participants were from two hospitals in Shandong, China.Participants 321 patients with lung cancer who underwent chemotherapy between April and September 2022 at two hospitals in Shandong province, China.Primary outcome measures The Family Hardiness Index, Cognitive Emotion Regulation Questionnaire, Sense of Coherence Scale and Post-Traumatic Growth Inventory.Results PTG was positively associated with FH (r=0.33, p<0.01), PCER (r=0.31, p<0.01) and SOC (r=0.37, p<0.01). FH was positively associated with PCER (r=0.31, p<0.01) and SOC (r=0.40, p<0.01). PCER was positively associated with SOC (r=0.32, p<0.01). The mediation analysis showed that FH affected PTG (β=0.235, p<0.05) directly and indirectly through PCER and SOC (β=0.097, 0.142, p<0.05). The mediating effects of PCER and SOC accounted for 20.46% and 29.96%, respectively, of the total effect (FH → PTG).Conclusion PCER and SOC mediated the relationship between FH and PTG in patients with lung cancer undergoing chemotherapy. Thus, future interventional studies should consider PCER and SOC as targets for developing PTG in patients with lung cancer receiving chemotherapy.",
  "authors": [
    {
      "affiliations": [
        "Binzhou Medical University, Yantai, Shandong, China",
        "Dezhou Vocational and Technical College, Dezhou, Shandong, China"
      ],
      "name": "Na Liu"
    },
    {
      "affiliations": [
        "Binzhou Medical University, Yantai, Shandong, China"
      ],
      "name": "Huichen Zhang"
    },
    {
      "affiliations": [
        "Binzhou Medical University Affiliated Hospital, Binzhou, Shandong, China"
      ],
      "name": "Gao Lixia"
    },
    {
      "affiliations": [
        "Shandong College of Traditional Chinese Medicine, Yantai, Shandong, China"
      ],
      "name": "Xiaoqing Fang"
    },
    {
      "affiliations": [
        "Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, China"
      ],
      "name": "Qing Li"
    },
    {
      "affiliations": [
        "Binzhou Medical University Affiliated Hospital, Binzhou, Shandong, China"
      ],
      "name": "Min Li"
    },
    {
      "affiliations": [
        "Binzhou Medical University Affiliated Hospital, Binzhou, Shandong, China"
      ],
      "name": "Lin Wang"
    },
    {
      "affiliations": [
        "Binzhou Medical University Affiliated Hospital, Binzhou, Shandong, China"
      ],
      "name": "Kun Ma"
    },
    {
      "affiliations": [
        "Binzhou Medical University, Yantai, Shandong, China"
      ],
      "name": "Xuemei Ding"
    },
    {
      "affiliations": [
        "Binzhou Medical University, Yantai, Shandong, China"
      ],
      "name": "Xiaoli Zhang"
    }
  ],
  "title": "Impact of positive cognitive emotion regulation and sense of coherence in the relationship between family hardiness and post-traumatic growth in patients with lung cancer: a mediation analysis study in two tertiary hospitals of China",
  "uid": "9bfe619d-cf75-55a6-a5be-5536b8b7ef3d"
}
