{
  "abstract": "Despite revolutionary advances in genomic technologies, a persistent disconnect exists between research discoveries and clinical implementation. This translational gap stems from misaligned incentive and funding structures: researchers prioritise publications over clinical uptake, with funding ending at proof-of-concept; clinicians face time constraints and integration challenges; regulators struggle with rapidly evolving technologies and genomics-specific complexities including variant classification and data governance. We propose that dedicated translational medicine centres are essential to bridge this divide. These centres require multidisciplinary teams spanning clinician-scientists, regulatory affairs specialists, health economists, biostatisticians and bioinformaticians, providing end-to-end support from feasibility assessment through to regulatory approval. Success requires government investment, explicit health equity assessments and measuring achievement through clinical uptake rather than traditional academic metrics.",
  "authors": [
    {
      "affiliations": [
        "Centre for Tropical Bioinformatics and Molecular Biology",
        "College of Science and Engineering, James Cook University, Cairns, Queensland, Australia"
      ],
      "name": "Andrew Calcino"
    },
    {
      "affiliations": [
        "Centre for Tropical Bioinformatics and Molecular Biology",
        "College of Science and Engineering, James Cook University, Cairns, Queensland, Australia",
        "Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia"
      ],
      "name": "Matt Field"
    }
  ],
  "title": "Lost in translation: why genomic breakthroughs are not reaching patients",
  "uid": "e1b8f03e-93b5-5da7-be30-b747c9e54131"
}