{
  "abstract": "Mucormycosis is a rare but aggressive fungal infection that can closely mimic neurological and vascular conditions, leading to significant diagnostic challenges. This opportunistic infection primarily affects immunocompromised individuals, particularly those with diabetes mellitus, and demonstrates a predilection for vascular invasion, causing thrombosis, ischemia, and rapid tissue necrosis. Despite aggressive treatment, prognosis remains poor, with high mortality and long-term neurological sequelae in survivors.We present the case of a woman in her late 40s who developed persistent left frontotemporal headache, raised inflammatory markers, and trigeminal neuralgia, initially suspected to have giant cell arteritis. However, her lack of response to corticosteroid therapy prompted further imaging, revealing an infiltrative process in the left pterygopalatine fossa, skull base, and infra-temporal fossa. Sinus biopsy confirmed mucormycosis with perineural spread, illustrating how this infection can closely resemble vasculitic neuropathy.The patient was treated with IV liposomal amphotericin, later escalated to a combination of amphotericin and posaconazole due to disease progression. Despite radiological stabilisation, she suffered persistent neuropathic symptoms. This case underscores the importance of considering fungal infections in atypical headache syndromes with cranial neuropathy, particularly in at-risk populations. Mucormycosis is a neurological emergency with devastating outcomes if not promptly recognised. Early multidisciplinary intervention, including targeted antifungal therapy and surgical debridement, remains crucial in mitigating morbidity and mortality.",
  "authors": [
    {
      "affiliations": [
        "Neurology, Royal Perth Hospital, Perth, WA, Australia",
        "Neurology, Fiona Stanley Hospital, Perth, WA, Australia"
      ],
      "name": "Ravi Ambati"
    },
    {
      "affiliations": [
        "Neurosciences Unit, Perron Institute for Neurological and Translational Science, Perth, WA, Australia"
      ],
      "name": "David Prentice"
    }
  ],
  "title": "3670 Mucormycosis with perineural spread: a rare mimic of vasculitic neuropathy",
  "uid": "d7f48229-eae5-5720-8c7e-08d46f3956bf"
}