{
  "abstract": "Background Evidence impact of the COVID-19 pandemic on health-related indicator in Sub-Saharan Africa is limited. We aimed to assess the indirect effect of COVID-19 on essential health service and outcomes in Guinea.Methods In this interrupted time series analysis, we analysed a nationally surveillance data from January 2018 to December 2022 of nine indicators of HIV, malaria, tuberculosis (TB) and childhood vaccination. We fitted a Poisson segmented regression model accounting for seasonality to estimate the immediate impact of the COVID-19 on these outcomes as well as per-pandemic trend through incidence rate ratio (IRRs) with 95% CIs.Results Between January 2018 and December 2022, the month-to-month (quarter-to-quarter for TB) changes before COVID-19 outbreak increased from 0.4% to 6.4% in all indicators except for TB therapeutic success rate (IRR 0.995, 95% CI 0.987 to 1.004). Overall, there was a decrease in three indicators ranging from 6% for pentavalent vaccine (IRR 0.940, 0.906 to 0.974) to 15% for TB total cases notification (IRR 0.850, 0.785 to 0.920). The pandemic COVID-19 trend significantly downward monthly for four indicators ranging from 0.8% for in-patient malaria cases (IRR 0.992, 0.986 to 0.998) to 8% for PCR test in infants (IRR 0.920, 0.902 to 0.938), and significantly increased monthly by 2.5% for TB-positive microscopy (IRR 1.025, 1.015 to 1.036) and by 0.9% for TB therapeutic success rate (IRR 1.009, 1.001 to 1.017).Conclusion In Guinea, during the 2020 COVID-19 pandemic, the malaria indicators were generally maintained, while the number of HIV tests in infants, childhood vaccines and TB indicators were heavily impacted. There is an urgent need for more protective and targeted strategies to improve the preparedness of the healthcare service.",
  "authors": [
    {
      "affiliations": [
        "Department of Public Health, Gamal Abdel Nasser University of Conakry, Conakry, Guinea"
      ],
      "name": "Alhassane Diallo"
    },
    {
      "affiliations": [
        "Public health Department, University of Conakry, Universite Gamal Abdel Nasser de Conakry Faculte des Sciences et Techniques de la Sante, Conakry, Guinea"
      ],
      "name": "Sidibe Sidikiba"
    },
    {
      "affiliations": [
        "Direction nationale de l’épidémiologie et de la lutte contre les maladies, Conakry, Guinée, Conakry, Guinea"
      ],
      "name": "Aboubacar Sidiki Cissé"
    },
    {
      "affiliations": [
        "Faculté des Sciences et Techniques de la Santé, Université Gamal Abdel Nasser de Conakry, Conakry, Guinée, Conakry, Guinea"
      ],
      "name": "Mohamed Camara"
    },
    {
      "affiliations": [
        "Direction nationale de l’épidémiologie et de la lutte contre les maladies, Conakry, Guinée, Conakry, Guinea"
      ],
      "name": "Mohamed Kaba"
    },
    {
      "affiliations": [
        "Faculté des Sciences et Techniques de la Santé, Université Gamal Abdel Nasser de Conakry, Service de Pneumo-Phtisiologie, CHU Conakry, Hôpital National Ignace Deen de Conakry, Conakry, Guinée, Conakry, Guinea"
      ],
      "name": "Boubacar Djelo Diallo"
    },
    {
      "affiliations": [
        "Department of Public Health, Gamal Abdel Nasser University of Conakry, Conakry, Guinea"
      ],
      "name": "Miguel Carlos-Bolumbu"
    },
    {
      "affiliations": [
        "Direction nationale de l’épidémiologie et de la lutte contre les maladies, Conakry, Guinée, Conakry, Guinea"
      ],
      "name": "Fodé Bangaly Sako"
    },
    {
      "affiliations": [
        "Centre d’Excellence d’Afrique (CEA-PCMT), Faculté des Sciences et Techniques de la Santé, Université Gamal Abdel Nasser de Conakry, Centre national de formation et de recherche en santé rurale de Maferinyah, Forecariah, Conakry, Guinea"
      ],
      "name": "Alexandre Delamou"
    }
  ],
  "title": "The impact of the COVID-19 pandemic on HIV, malaria, tuberculosis and childhood vaccination services in Guinea: an interrupted time series analysis",
  "uid": "49489765-cc66-588c-897e-adcaed424b7f"
}