{
  "abstract": "Child mortality disproportionally clusters in low- and middle-income countries (LMICs), with the highest burden in sub-Saharan Africa, where under-five mortality peaks at 69 deaths per 1000 live births compared with the average global mortality rate of 37 per 1000 live births. 1 The leading primary causes of postneonatal deaths in children aged 1–59 months are lower respiratory tract infections, malaria and diarrhoea, which collectively cause one-third of under-five deaths.1 2 Several interventions with demonstrated efficacy to reduce child mortality exist, such as vaccination, early diagnosis of pneumonia and access to medical oxygen. However, their widespread implementation is often hindered by the fragility of health systems in such settings. Integration of effective interventions into care pathways also affects their potential to impact on child outcomes, and this is particularly the case at the lowest levels of care—such as within primary healthcare (PHC) facilities or at the community level, where care is typically delivered by community health workers or village health teams. Missed hypoxaemia remains a major cause of preventable mortality in children. Integrating pulse oximetry (PO) into the Integrated Management of Childhood Illnesses (IMCI) offers a critical opportunity to improve early detection of severe illness, but findings from the Amélioration de l’Identification des Détresses Respiratoires chez l’Enfant (AIRE) project show that successful implementation requires supportive health system reforms.",
  "authors": [
    {
      "affiliations": [
        "August Pi i Sunyer Biomedical Research Institute–IDIBAPS, Barcelona, Spain",
        "Ciber de Enfermedades Respiratorias (CIBERES), Barcelona, Spain",
        "Faculty of Health Sciences, Continental University, Huancayo, Peru"
      ],
      "name": "Catia Cilloniz"
    },
    {
      "affiliations": [
        "Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Maputo, Mozambique"
      ],
      "name": "Sergio Massora"
    },
    {
      "affiliations": [
        "Child Health and Development Center, College of Health Sciences, Makerere University, Kampala, Uganda",
        "Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain"
      ],
      "name": "Anthony Batte"
    },
    {
      "affiliations": [
        "Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Maputo, Mozambique",
        "Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain",
        "ISGlobal, Barcelona, Spain",
        "ICREA, Pg. Lluís Companys 23, 08010, Barcelona, Spain",
        "Institut Clínic de Medicina I Dermatologia, Hospital Clínic de Barcelona, Barcelona, Spain",
        "Pediatrics Department, Hospital Sant Joan de Déu, Barcelona, Spain",
        "CIBER de Epidemiología y Salud Pública, Instituto de Salud Carlos III, Madrid, Spain"
      ],
      "name": "Quique Bassat"
    }
  ],
  "title": "Pulse oximetry to optimise first-line care and save children’s lives: evidence from the AIRE project in West Africa",
  "uid": "53650ca1-a830-53bc-a84e-52043c3db870"
}