{
  "abstract": "The incidence of incidental pancreatic cystic lesions (PCLs) has risen in recent years, largely due to advances in and increased use of imaging techniques. Endoscopic ultrasound (EUS) has become a crucial tool for evaluating and characterising PCLs, allowing for detailed morphological assessment and aiding in the identification of lesions with a higher risk of progression to high-grade dysplasia or invasive pancreatic carcinoma. This review aims to outline the key aspects of EUS in the evaluation of PCLs, covering a range of modalities from morphological assessment and contrast-enhanced imaging to elastography, fine-needle aspiration for biomarker analysis, cytology, DNA sequencing, histological evaluation and the emerging role of confocal laser endomicroscopy or artificial intelligence. Additionally, we address therapeutic EUS modalities for PCLs, the current limitations of EUS, anticipated technological advancements and the diverse management strategies recommended by leading scientific societies for the clinical handling of PCLs.",
  "authors": [
    {
      "affiliations": [
        "Gastroenterology Department, Dr. Balmis General University Hospital, Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain"
      ],
      "name": "Lucía Guilabert"
    },
    {
      "affiliations": [
        "Department of Gastroenterology, University Medical Centre Maribor, Maribor, Slovenia"
      ],
      "name": "Sara Nikolìc"
    },
    {
      "affiliations": [
        "Gastroenterology Department, Dr. Balmis General University Hospital, Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain"
      ],
      "name": "Enrique de-Madaria"
    },
    {
      "affiliations": [
        "Pancreato-Biliary Endoscopy and Endosonography Division,Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Milan, Italy",
        "Vita-Salute San Raffaele University, Milan, Italy"
      ],
      "name": "Giuseppe Vanella"
    },
    {
      "affiliations": [
        "Pancreato-Biliary Endoscopy and Endosonography Division,Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Milan, Italy",
        "Vita-Salute San Raffaele University, Milan, Italy"
      ],
      "name": "Gabriele Capurso"
    },
    {
      "affiliations": [
        "Pancreato-Biliary Endoscopy and Endosonography Division,Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Milan, Italy",
        "Vita-Salute San Raffaele University, Milan, Italy"
      ],
      "name": "Matteo Tacelli"
    },
    {
      "affiliations": [
        "Department of Medicine and Surgery, University of Enna ‘Kore’, Enna, Italy",
        "Gastroenterology Unit, Umberto I Hospital, Enna, Italy"
      ],
      "name": "Marcello Maida"
    },
    {
      "affiliations": [
        "\"Agrippa Ionescu” Clinical Emergency Hospital, Bucharest, Romania",
        "\"Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania"
      ],
      "name": "Catalina Vladut"
    },
    {
      "affiliations": [
        "Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases, Aalborg University Hospital, Aalborg, Denmark"
      ],
      "name": "Cecilie Siggaard Knoph"
    },
    {
      "affiliations": [
        "Gastroenterology and Endoscopy Unit, Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione (ISMETT-IRCCS), Palermo, Italy"
      ],
      "name": "Dario Quintini"
    },
    {
      "affiliations": [
        "Gastroenterology and Endoscopy Unit, Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione (ISMETT-IRCCS), Palermo, Italy"
      ],
      "name": "Gabriele Rancatore"
    },
    {
      "affiliations": [
        "Gastroenterology and Endoscopy Unit, Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione (ISMETT-IRCCS), Palermo, Italy"
      ],
      "name": "Giuseppe Infantino"
    },
    {
      "affiliations": [
        "Gastroenterology and Endoscopy Unit, Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione (ISMETT-IRCCS), Palermo, Italy"
      ],
      "name": "Ilaria Tarantino"
    },
    {
      "affiliations": [
        "Gastroenterology and Endoscopy Unit, Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione (ISMETT-IRCCS), Palermo, Italy"
      ],
      "name": "Giacomo Emanuele Maria Rizzo"
    }
  ],
  "title": "Endoscopic ultrasound for pancreatic cystic lesions: a narrative review",
  "uid": "4fdf1d6c-5122-5586-8e09-2be1dc3c277d"
}