{
  "abstract": "A woman in her 60s with a prior history of cervical carcinoma treated with chemoradiation presented with a polypoidal vaginal lesion nearly 7 years after initial therapy. Histopathology confirmed osteosarcoma confined to the posterior vaginal wall, with imaging excluding metastases. Total vaginectomy was performed, and final diagnosis was radiation-induced vaginal osteosarcoma. Although adjuvant chemotherapy was recommended, the patient declined. 6 months later, local recurrence and lung metastases developed. This case highlights the rare occurrence of radiation-induced osteosarcoma at the vaginal vault, emphasising the importance of long-term surveillance following pelvic radiotherapy for gynaecological malignancies.",
  "authors": [
    {
      "affiliations": [
        "Department of Surgical Oncology, Cancer Institute WIA and Research Centre, Chennai, Tamil Nadu, India"
      ],
      "name": "Saravanan Moorthy"
    },
    {
      "affiliations": [
        "Department of Surgical Oncology, Cancer Institute WIA and Research Centre, Chennai, Tamil Nadu, India"
      ],
      "name": "Ellusamy Hemant Raj"
    },
    {
      "affiliations": [
        "Department of Onco-Pathology, Cancer Institute WIA and Research Centre, Chennai, Tamilnadu, India"
      ],
      "name": "Shirley Sundersingh"
    },
    {
      "affiliations": [
        "Department of Surgical Oncology, Cancer Institute WIA and Research Centre, Chennai, Tamil Nadu, India"
      ],
      "name": "Anand Raja"
    }
  ],
  "title": "Radiation-induced Osteosarcoma of the vaginal vault following cervical cancer treatment",
  "uid": "4339aa87-e09e-573b-8d96-47d74c9cbeb9"
}