{
  "abstract": "A primigravida at 26 weeks’ gestation visiting from Pakistan presented with fever, abdominal pain and hypotension suggestive of sepsis and required admission to the intensive care unit. Blood culture grew a multidrug-resistant (MDR) Salmonella enterica serovar Typhi isolate that was resistant to cephalosporins but susceptible to carbapenems. Intravenous meropenem was commenced, resulting in a rapid clinical improvement within 48 hours. She completed a 14-day course of meropenem without maternal or fetal adverse effects, and repeat blood cultures were sterile. The remainder of her pregnancy was uncomplicated, and she delivered a healthy term infant. This case highlights the diagnostic and therapeutic challenges of MDR, cephalosporin-resistant Salmonella Typhi infection during pregnancy and supports meropenem as an effective and potentially life-saving treatment associated with favourable maternal and fetal outcomes.",
  "authors": [
    {
      "affiliations": [
        "Ohud Hospital, Medina, Al Madinah Province, Saudi Arabia"
      ],
      "name": "Abdurhman Alalowi"
    },
    {
      "affiliations": [
        "Ohud Hospital, Medina, Al Madinah Province, Saudi Arabia"
      ],
      "name": "Abrar Alahmadi"
    },
    {
      "affiliations": [
        "King Salman bin Abdulaziz Medical City, Medina, Al Madinah Province, Saudi Arabia"
      ],
      "name": "Ahmad Aljabri"
    },
    {
      "affiliations": [
        "Ohud Hospital, Medina, Al Madinah Province, Saudi Arabia"
      ],
      "name": "Mohammed Khoja"
    }
  ],
  "title": "Ceftriaxone-resistant multidrug-resistant Salmonella Typhi sepsis in pregnancy",
  "uid": "9315792e-9629-57a0-af6a-5abf9bcc62a1"
}