{
  "abstract": "A previously healthy woman in her 30s presented with high-grade fever, photophobia and fluctuating consciousness, and was diagnosed with herpes simplex virus type 1\\ encephalitis. Her condition deteriorated, requiring intensive care support for type 1 respiratory failure. During her intensive care unit stay, she was found to have significant left ventricular systolic dysfunction with basal-mid akinesia and apical sparing on echocardiography. Cardiac MRI demonstrated features consistent with stress-induced (Takotsubo) cardiomyopathy. She made a complete neurological and cardiac recovery with supportive care, antiviral therapy and temporary heart-failure therapy. This case highlights the importance of considering cardiac involvement in severe encephalitis and the multidisciplinary management required for rare neuro-cardiac interactions.",
  "authors": [
    {
      "affiliations": [
        "North West Anglia NHS Foundation Trust, Peterborough, UK"
      ],
      "name": "Alex Mathew"
    },
    {
      "affiliations": [
        "North West Anglia NHS Foundation Trust, Peterborough, UK"
      ],
      "name": "Rosily Thomas"
    },
    {
      "affiliations": [
        "North West Anglia NHS Foundation Trust, Peterborough, UK"
      ],
      "name": "Aalekh Prasad"
    }
  ],
  "title": "Severe herpes simplex virus encephalitis complicated by atypical Takotsubo cardiomyopathy with left ventricular systolic dysfunction",
  "uid": "100e9e03-e221-554e-8ca7-dd557956bbe4"
}