{
  "abstract": "A woman in her 60s with a history of atrial fibrillation, hypertension and dyslipidaemia was admitted to the Intensive Care Unit with hypotension, dehydration and acute kidney injury after 20 days of watery diarrhoea. Although initial investigations did not detect an evident infectious aetiology, a diagnosis of infectious colitis was hypothesised. After supportive care and quick recovery, she was discharged and instructed to resume her prior medications, including olmesartan (used for 1 year) for hypertension. Diarrhoea and renal failure recurred promptly, leading to readmission. Gastroscopy revealed severe villous atrophy and inflammation of the duodenum. However, serological tests for coeliac disease were negative. Olmesartan-related sprue-like enteropathy was diagnosed after discontinuing olmesartan, leading to clinical improvement without a gluten-free diet. This case emphasised the importance of considering iatrogenic causes in severe enteropathy differential diagnosis, particularly olmesartan-related complications in patients presenting with sprue-like symptoms, watery diarrhoea and acute renal failure.",
  "authors": [
    {
      "affiliations": [
        "Department of Medicine, Unit of Internal Medicine B, University of Verona School of Medicine, Azienda Ospedaliera Universitaria Integrata Verona, Policlinico \"G.B. Rossi\", University of Verona, Verona, Veneto, Italy"
      ],
      "name": "Silvia Suardi"
    },
    {
      "affiliations": [
        "Department of Medicine, Unit of Internal Medicine B, University of Verona School of Medicine, Azienda Ospedaliera Universitaria Integrata Verona, Policlinico \"G.B. Rossi\", University of Verona, Verona, Veneto, Italy"
      ],
      "name": "Marco Vicardi"
    },
    {
      "affiliations": [
        "Department of Medicine, Unit of Internal Medicine B, University of Verona School of Medicine, Azienda Ospedaliera Universitaria Integrata Verona, Policlinico \"G.B. Rossi\", University of Verona, Verona, Veneto, Italy"
      ],
      "name": "Carlotta Spillere"
    },
    {
      "affiliations": [
        "Department of Medicine, Unit of Internal Medicine B, University of Verona School of Medicine, Azienda Ospedaliera Universitaria Integrata Verona, Policlinico \"G.B. Rossi\", University of Verona, Verona, Veneto, Italy"
      ],
      "name": "Paola Leidi"
    },
    {
      "affiliations": [
        "Department of Diagnostic and Public Health, Section of Pathology, University of Verona, Verona, Veneto, Italy"
      ],
      "name": "Sara Pecori"
    },
    {
      "affiliations": [
        "Gastroenterology Unit, Department of Medicine, University of Verona, Verona, Veneto, Italy"
      ],
      "name": "Pietro Campagnola"
    },
    {
      "affiliations": [
        "Department of Medicine, Unit of Internal Medicine B, University of Verona School of Medicine, Azienda Ospedaliera Universitaria Integrata Verona, Policlinico \"G.B. Rossi\", University of Verona, Verona, Veneto, Italy"
      ],
      "name": "Simonetta Friso"
    },
    {
      "affiliations": [
        "Department of Medicine, Unit of Internal Medicine B, University of Verona School of Medicine, Azienda Ospedaliera Universitaria Integrata Verona, Policlinico \"G.B. Rossi\", University of Verona, Verona, Veneto, Italy"
      ],
      "name": "Nicola Martinelli"
    }
  ],
  "title": "Olmesartan-related sprue-like enteropathy presenting as severe diarrhoea",
  "uid": "c7e1b459-b516-52e6-a7c3-c075c8759730"
}