{
  "abstract": "A small proportion of small cell lung cancer (SCLC) presents as paraneoplastic limbic encephalitis (PLE). The most implicated antibody is anti-Hu, but others such as anti-ampiphysin, anti-CRMP5 and anti-SOX1 have been frequently detected. Autoimmune encephalitis mediated by antibodies against α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) is a rare but important neurological complication of SCLC. The incidence of SCLC presenting with anti-AMPAR antibody PLE is extremely low. Our case illustrates a rare presentation of SCLC with an intention to highlight the importance of evaluating for malignancy and associated paraneoplastic syndromes in patients with unexplained encephalopathy.",
  "authors": [
    {
      "affiliations": [
        "Internal Medicine, University of Kentucky, Lexington, Kentucky, USA"
      ],
      "name": "Chandra L Kakarala"
    },
    {
      "affiliations": [
        "Neurology, University of Kentucky, Lexington, Kentucky, USA"
      ],
      "name": "Vishal Mehta"
    },
    {
      "affiliations": [
        "University of Kentucky, Lexington, Kentucky, USA"
      ],
      "name": "Nicole Lisek"
    },
    {
      "affiliations": [
        "University of Kentucky, Lexington, Kentucky, USA"
      ],
      "name": "Zhonglin Hao"
    }
  ],
  "title": "Anti-AMPAR limbic encephalitis as the initial presentation of metastatic small cell cancer",
  "uid": "3eb9e9d0-b3a9-57ca-a88c-e6b96b21ea58"
}